Easy Stress Relief by EZH2

被引：1
|
作者：
Prasanth, Supriya G. [1 ]
Prasanth, Kannanganattu V. [1 ]
机构：
[1] Univ Illinois, Dept Cell & Dev Biol, 601 South Goodwin Ave, Urbana, IL 61801 USA
来源：
CELL | 2016年 / 167卷 / 07期
基金：
美国国家科学基金会;
关键词：
RNA-POLYMERASE-II; NONCODING RNAS; B2; RNA; TRANSCRIPTION; GENOME;
D O I：
10.1016/j.cell.2016.11.051
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
While we are beginning to appreciate the cellular roles played by long noncoding RNAs, the function of transcripts emerging from repetitive genomic regions remains enigmatic. In this issue, Zovoilis et al. report that the polycomb protein EZH2, upon heat shock, facilitates transcription of stressresponsive genes by inducing the degradation of the transcriptional repressor B2 repeat RNA.
引用
收藏
页码：1678 / 1680
页数：4
相关论文
共 50 条
  • [1] EZH2: Not EZHY (Easy) to Deal
    Deb, Gauri
    Singh, Anup Kumar
    Gupta, Sanjay
    MOLECULAR CANCER RESEARCH, 2014, 12 (05) : 639 - 653
  • [2] Hypoxia makes EZH2 inhibitor not easy——advances of crosstalk between HIF and EZH2
    Zhanya Huang
    Yuanjun Tang
    Jianlin Zhang
    Jiaqi Huang
    Rui Cheng
    Yunyun Guo
    Celina GKleer
    Yuqing Wang
    Lixiang Xue
    Life Metabolism, 2024, 3 (04) : 17 - 26
  • [3] Hypoxia makes EZH2 inhibitor not easy-advances of crosstalk between HIF and EZH2
    Huang, Zhanya
    Tang, Yuanjun
    Zhang, Jianlin
    Huang, Jiaqi
    Cheng, Rui
    Guo, Yunyun
    Kleer, Celina G.
    Wang, Yuqing
    Xue, Lixiang
    LIFE METABOLISM, 2024, 3 (04):
  • [4] Epigenetics in lymphocyte and lymphoma: EZH2 as an easy-to-access therapeutic target?
    Kato, Koji
    INTERNATIONAL JOURNAL OF HEMATOLOGY, 2022, 116 (06) : 819 - 820
  • [5] Epigenetics in lymphocyte and lymphoma: EZH2 as an easy-to-access therapeutic target?
    Koji Kato
    International Journal of Hematology, 2022, 116 : 819 - 820
  • [6] Epigenetic Targeting with EZH2 and HDAC Inhibitors Is Synergistic in EZH2 Deregulated Lymphomas
    Lue, Jennifer Kimberly
    Prabhu, Sathyen A.
    Liu, Yuxuan
    O'Connor, Owen A.
    Amengual, Jennifer E.
    BLOOD, 2016, 128 (22)
  • [7] THE ROLE OF EZH2 IN MEDULLOBLASTOMA
    Sola, Ismail
    Venktaraman, Sujatha
    Balakrishnan, Ilongo
    Birks, Diane
    Foreman, Nicholas
    Vibhakar, Rajeev
    NEURO-ONCOLOGY, 2016, 18 : 113 - 113
  • [8] Targeting EZH2 in cancer
    Kimberly H Kim
    Charles W M Roberts
    Nature Medicine, 2016, 22 : 128 - 134
  • [9] Targeting EZH2 with tazemetostat
    Makita, Shinichi
    Tobinai, Kensei
    LANCET ONCOLOGY, 2018, 19 (05): : 586 - 587
  • [10] EZH2 Goes Solo
    Cavalli, Giacomo
    SCIENCE, 2012, 338 (6113) : 1430 - 1431
12345