Artificial Molecular Machines in Nanotheranostics

被引：71

作者：

Yu, Guocan ^{[1
]}

Yung, Bryant C. ^{[1
]}

Zhou, Zijian ^{[1
]}

Mao, Zhengwei ^{[2
]}

Chen, Xiaoyuan ^{[1
]}

机构：

[1] Natl Inst Biomed Imaging & Bioengn, Lab Mol Imaging & Nanomed, NIH, Bethesda, MD 20892 USA

[2] Zhejiang Univ, Dept Polymer Sci & Engn, MOE Key Lab Macromol Synth & Functionalizat, Hangzhou 310027, Zhejiang, Peoples R China

来源：

ACS NANO | 2018年 / 12卷 / 01期

基金：

美国国家卫生研究院; 中国国家自然科学基金;

关键词：

DRUG-DELIVERY; SILICA NANOPARTICLES; MESOPOROUS SILICA; ANTICANCER DRUG; IN-VIVO; SYSTEMS; THERAPY; MOTORS; TRANSPORTERS; STRATEGIES;

D O I：

10.1021/acsnano.7b07851

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Due to their dynamic nature and excellent stimuli-responsiveness resulting from noncovalent driving forces, artificial molecular machines (AMMs) show great promise in cancer theranostics. In this Perspective, we introduce the potential applications of AMMs in controlled drug delivery, bioorthogonal catalysis, imaging, and cell membrane permeabilization, with the goal of enhancing cancer diagnosis and therapy. We expect this preliminary discussion will gamer multidisciplinary interest from scientists to advance AMMs and to expand their fixture clinical applications.

引用

页码：7 / 12

页数：6

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