Diabetic Kidney Disease

被引:147
|
作者
Bonner, Ryan [1 ,2 ]
Albajrami, Oltjon [1 ,2 ]
Hudspeth, James [1 ,2 ]
Upadhyay, Ashish [1 ,2 ]
机构
[1] Boston Med Ctr, Dept Med, Sect Nephrol, 800 Harrison Ave,G009, Boston, MA 02118 USA
[2] Boston Univ, Sch Med, 800 Harrison Ave,G009, Boston, MA 02118 USA
来源
PRIMARY CARE | 2020年 / 47卷 / 04期
关键词
Diabetic kidney disease; Diabetic nephropathy; Chronic kidney disease; Albuminuria; RENIN-ANGIOTENSIN SYSTEM; CARDIOVASCULAR OUTCOMES; ACE-INHIBITION; DOUBLE-BLIND; THERAPEUTIC TARGET; GLUCOSE CONTROL; RENAL OUTCOMES; DUAL BLOCKADE; TYPE-2; NEPHROPATHY;
D O I
10.1016/j.pop.2020.08.004
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Diabetic kidney disease (DKD) is the most common cause of chronic kidney disease in the United States. Approximately 30% to 40% of individuals with diabetes mellitus develop DKD, and the presence of DKD significantly elevates the risk for morbidity and mortality. Understanding of DKD has grown in recent years. This review describes the pathogenesis of DKD and expands on evidence-based strategies for DKD management, integrating traditional approaches for hyperglycemia, hypertension, and albuminuria management with emerging therapeutic options. Given the public health burden of DKD, it is essential to prioritize prevention, recognition, and management of DKD in the primary care setting.
引用
收藏
页码:645 / 659
页数:15
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