In-vivo multilaboratory investigation of the optical properties of the human head

被引：49

作者：

Farina, Andrea ^{[1
]}

Torricelli, Alessandro ^{[2
]}

Bargigia, Ilaria ^{[3
]}

Spinelli, Lorenzo ^{[1
]}

Cubeddu, Rinaldo ^{[2
]}

Foschum, Florian ^{[3
]}

Jaeger, Marion ^{[3
]}

Simon, Emanuel ^{[3
]}

Fugger, Oliver ^{[3
]}

Kienle, Alwin ^{[3
]}

Martelli, Fabrizio ^{[4
]}

Di Ninni, Paola ^{[4
]}

Zaccanti, Giovanni ^{[4
]}

Milej, Daniel ^{[5
]}

Sawosz, Piotr ^{[5
]}

Kacprzak, Michal ^{[5
]}

Liebert, Adam ^{[5
]}

Pifferi, Antonio ^{[1
,2
]}

机构：

[1] CNR, Ist Foton & Nanotecnol, I-20133 Milan, Italy

[2] Politecn Milan, POLIMI, Dipartimento Fis, I-20133 Milan, Italy

[3] Ctr Nanosci & Technol POLIMI, Ist Italiano Tecnol, I-20133 Milan, Italy

[4] Univ Ulm, ILM, Inst Lasertechnol Med & Messtech, D-89081 Ulm, Germany

[5] Univ Florence, UNIFI, Dipartimento Fis & Astron, I-50019 Florence, Italy

来源：

BIOMEDICAL OPTICS EXPRESS | 2015年 / 6卷 / 07期

关键词：

NEAR-INFRARED SPECTROSCOPY; TIME-RESOLVED MEASUREMENTS; CEREBROSPINAL-FLUID LAYER; ADULT HEAD; LIGHT-PROPAGATION; HUMAN BRAIN; PHOTON MIGRATION; NONINVASIVE DETERMINATION; TURBID MEDIA; MODEL;

D O I：

10.1364/BOE.6.002609

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The in-vivo optical properties of the human head are investigated in the 600-1100 nm range on different subjects using continuous wave and time domain diffuse optical spectroscopy. The work was performed in collaboration with different research groups and the different techniques were applied to the same subject. Data analysis was carried out using homogeneous and layered models and final results were also confirmed by Monte Carlo simulations. The depth sensitivity of each technique was investigated and related to the probed region of the cerebral tissue. This work, based on different validated instruments, is a contribution to fill the existing gap between the present knowledge and the actual in-vivo values of the head optical properties. (C) 2015 Optical Society of America

引用

页码：2609 / 2623

页数：15

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