Novel laminin-binding protein of Streptococcus pyogenes, Lbp, is involved in adhesion to epithelial cells

被引：0
|
作者：
Terao, Y [1 ]
Kawabata, S [1 ]
Kunitomo, E [1 ]
Nakagawa, I [1 ]
Hamada, S [1 ]
机构：
[1] Osaka Univ, Fac Dent, Dept Oral Microbiol, Suita, Osaka 5650871, Japan
来源：
INFECTION AND IMMUNITY | 2002年 / 70卷 / 02期
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中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The lbp gene, which encodes a laminin-binding protein (Lbp) of Streptococcus pyogenes, was found in all S. pyogenes M types. An Lbp-deficient mutant showed a significant, lower efficiency of adhesion to HEp-2 cells than did the wild-type strain. These results indicate that Lbp is one of the important S. pyogenes adhesins.
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页码：993 / 997
页数：5
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