Structural properties of aqueous metoprolol succinate solutions. Density, viscosity, and refractive index at 311 K

被引:14
|
作者
Deosarkar, S. D. [1 ]
Kalyankar, T. M. [2 ]
机构
[1] Swami Ramanand Teerth Marathwada Univ, Sch Chem Sci, Nanded 431606, MS, India
[2] Swami Ramanand Teerth Marathwada Univ, Sch Pharm, Nanded 431606, MS, India
关键词
metoprolol succinate; apparent molar volume; molecular interactions; APPARENT MOLAR VOLUME; ADIABATIC COMPRESSIBILITY; ION-SOLVENT; MIXTURES; WATER; T=298.15; ACID;
D O I
10.1134/S0036024413060356
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Density, viscosity and refractive index of aqueous solutions of metoprolol succinate of different concentrations (0.005-0.05 mol dm(-3)) were measured at 38A degrees C. Apparent molar volume of resultant solutions were calculated and fitted to the Masson's equation and apparent molar volume at infinite dilution was determined graphically. Viscosity data of solutions has been fitted to the Jone-Dole equation and viscosity A- and B-coefficients were determined graphically. Physicochemical data obtained were discussed in terms of molecular interactions.
引用
收藏
页码:1060 / 1062
页数:3
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