Secukinumab exploratory study to investigate distribution in dermal interstitial fluid using dermal open flow microperfusion after single 300-mg subcutaneous administration: Pharmacokinetic assessment in healthy volunteers and patients with moderate to severe plaque-type psoriasis

被引:0
|
作者
Bruin, Gerard [1 ]
Loesche, Christian [2 ]
Calonder, Claudio [2 ]
Polus, Florine [2 ]
Sinner, Frank [3 ]
机构
[1] Novartis Pharma AG, Basel, Switzerland
[2] Novartis Inst BioMed Res, Basel, Switzerland
[3] Inst Biomed & Hlth Sci Bei Joanneum Res, Graz, Austria
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D O I
暂无
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
P8110
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页码:AB187 / AB187
页数:1
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  • [1] The anti IL-17A IgG1 antibody distributes in dermal interstitial fluid as demonstrated by using dermal open flow microperfusion after a single 300 mg subcutaneous administration; assessment in healthy volunteers and patients with moderate-to-severe plaque psoriasis
    Bruin, G.
    Dragatin, C.
    Aigner, B.
    Polus, F.
    Calonder, C.
    Froeliger, C.
    Tiffner, K.
    Bodenlenz, M.
    Mader, J.
    Korsatko, S.
    Ratzer, M.
    Pieber, T.
    Loesche, C.
    Sinner, F.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2014, 134 : S18 - S18