Studies on total synthesis of the cylindricine/fasicularin/lepadiformine family of tricyclic marine alkaloids

被引：130
|
作者：
Weinreb, SM [1 ]
机构：
[1] Penn State Univ, Dept Chem, University Pk, PA 16802 USA
来源：
CHEMICAL REVIEWS | 2006年 / 106卷 / 06期
关键词：
D O I：
10.1021/cr050069v
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
This review covers the isolation of a family of structurally related tricyclic alkaloids. Topics discussed include the isolation and structure determination, biological activity, synthetic approaches to the cylindricines, synthesis of fasicularin, and synthesis and structure determination of lepadiformine. Furthermore, the Hsung synthesis of (-)-cylindricine C and the Renaud synthesis of (±)-lepadiformine are also considered.
引用
收藏
页码：2531 / 2549
页数：19
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