Body cell mass is a useful parameter for assessing malnutrition and severity of disease in non-ascitic cirrhotic patients with hepatocellular carcinoma or esophageal varices

被引：19

作者：

Kawaguchi, Takumi ^{[1
,2
]}

Taniguchi, Eitaro ^{[2
]}

Itou, Minoru ^{[2
]}

Ibi, Ryoko ^{[3
]}

Okada, Teruyo ^{[3
]}

Mutou, Michiko ^{[3
]}

Shiraishi, Satomi ^{[3
]}

Uchida, Yuki ^{[4
]}

Otsuka, Momoka ^{[4
]}

Umeki, Youko ^{[5
]}

Oriishi, Tetsuharu ^{[2
]}

Hayabuchi, Hitomi ^{[5
]}

Tanaka, Suiko ^{[4
]}

Takakura, Machiko ^{[3
]}

Sata, Michio ^{[1
,2
]}

机构：

[1] Kurume Univ, Dept Digest Dis Informat & Res, Sch Med, Kurume, Fukuoka 8300011, Japan

[2] Kurume Univ, Div Gastroenterol, Sch Med, Dept Med, Kurume, Fukuoka 8300011, Japan

[3] Kurume Univ Hosp, Dept Nursing, Kurume, Fukuoka, Japan

[4] Kurume Univ Hosp, Dept Nutr, Kurume, Fukuoka, Japan

[5] Fukuoka Womens Univ, Dept Nutr & Hlth Sci, Fac Human Environm Sci, Fukuoka, Japan

来源：

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE | 2008年 / 22卷 / 05期

关键词：

body composition; eight-polar bioelectrical impedance analyzer; nutritional assessment; liver disease; model for end-stage liver disease score;

D O I：

10.3892/ijmm_00000060

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Body cell mass (BCM) is a nutritional parameter, however, changes in BCM in patients with non-ascitic liver cirrhosis (LC) in comparison to patients with other malnutritional diseases remains unclear. We investigated the difference in BCM between patients with LC and malnourished gastrointestinal disease controls (M.CON), and examined the relationship between BCM and the severity of LC. Results demonstrated that serum nutritional parameters were not significantly different between the LC (n=56) and M.CON groups (n=25), whereas BCM%BW was significantly lower in the LC group than in the M.CON group (50.9 +/- 4.6 vs. 54.4 +/- 7.1%, P = 0.018). Furthermore, BCM%BW negatively correlated with the model for end-stage liver disease (MELD) score (P = 0.04). In concluson, BCM showed a significant decrease and a negative correlation with the MELD score in the LC group. BCM may be a useful parameter for assessing malnutrition and severity of LC.

引用

页码：589 / 594

页数：6