Valproate as a treatment for dopamine dysregulation syndrome (DDS) in Parkinson's disease

被引：27

作者：

Sriram, Ashok ^{[1
]}

Ward, Herbert E. ^{[2
]}

Hassan, Anhar ^{[1
]}

Iyer, Sanjay ^{[3
]}

Foote, Kelly D. ^{[4
]}

Rodriguez, Ramon L. ^{[1
]}

McFarland, Nikolaus R. ^{[1
]}

Okun, Michael S. ^{[1
,4
]}

机构：

[1] Ctr Movement Disorders & Neurorestorat, Dept Neurol, Gainesville, FL 32611 USA

[2] Ctr Movement Disorders & Neurorestorat, Dept Psychiat, Gainesville, FL 32611 USA

[3] CMC Neurol, Charlotte, NC USA

[4] Ctr Movement Disorders & Neurorestorat, Dept Neurosurg, Gainesville, FL 32611 USA

来源：

JOURNAL OF NEUROLOGY | 2013年 / 260卷 / 02期

关键词：

Dopamine dysregulation syndrome; Parkinson's disease; Impulse control disorder; Valproic acid; Dominion; HEDONISTIC HOMEOSTATIC DYSREGULATION; IMPULSE-CONTROL DISORDERS; DEEP BRAIN-STIMULATION; REPLACEMENT THERAPIES; SUBTHALAMIC NUCLEUS; SODIUM VALPROATE; COMPULSIVE USE; ACID; INHIBITION; NEURONS;

D O I：

10.1007/s00415-012-6669-1

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

It has been previously well established that the use of dopaminergic agents in Parkinson's disease may contribute to behavioral disturbances such as dopamine dysregulation syndrome (DDS), impulse control disorders (ICD), and punding. ICD and punding have been most commonly addressed by reducing dose or by discontinuing the use of a dopamine agonist. Treatment of DDS has proven more challenging, and to date there has been no standard approach. In this paper, we review a series of four patients who met criteria for DDS, who were all refractory to medication adjustments. The DDS symptoms responded by the addition of valproic acid in all cases.

引用

页码：521 / 527

页数：7

共 50 条

[1] Valproate as a treatment for dopamine dysregulation syndrome (DDS) in Parkinson’s disease
Ashok Sriram
Herbert E. Ward
Anhar Hassan
Sanjay Iyer
Kelly D. Foote
Ramon L. Rodriguez
Nikolaus R. McFarland
Michael S. Okun
Journal of Neurology, 2013, 260 : 521 - 527
[2] Dopamine dysregulation syndrome in Parkinson's disease
Borg, M.
Bayreuther, C.
REVUE NEUROLOGIQUE, 2008, 164 (04) : 310 - 321
[3] Dopamine dysregulation syndrome in Parkinson's disease
Evans, AH
Lees, AJ
CURRENT OPINION IN NEUROLOGY, 2004, 17 (04) : 393 - 398
[4] Addicted to dopamine - the dopamine dysregulation syndrome in Parkinson's disease
Evans, A. H.
EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2009, 19 : S196 - S196
[5] Prevalence of dopamine dysregulation syndrome in Parkinson's disease
Valenca, G.
Costa, R.
Glass, P.
Negreiros, N.
Almeida, L.
Oliveira-Filho, J.
MOVEMENT DISORDERS, 2012, 27 : S291 - S291
[6] Dopamine dysregulation syndrome (DDS)
不详
ACTUALITES PHARMACEUTIQUES, 2009, 48 (489): : 21 - 21
[7] Dopamine dysregulation syndrome in Parkinson's disease and restless legs syndrome
Bayard, Sophie
De Cock, Valerie Cochen
Dauvillers, Yves
GERIATRIE ET PSYCHOLOGIE NEUROPSYCHIATRIE DE VIEILLISSEMENT, 2011, 9 (02): : 227 - 235
[8] Dopamine dysregulation syndrome in Parkinson's disease - Case report
Kummer, Arthur
Maia, Debora Palma
Salgado, Joao Vinicius
Cardoso, Francisco E. C.
Teixeira, Antonio Lucio
ARQUIVOS DE NEURO-PSIQUIATRIA, 2006, 64 (04) : 1019 - 1022
[9] Addiction to levodopa: Dopamine dysregulation syndrome in Parkinson's disease
Pandey, S.
Mehndiratta, M.
MOVEMENT DISORDERS, 2012, 27 : S282 - S282
[10] Dopamine dysregulation syndrome in Parkinson's disease controlled by safinamine
Song, S. K.
Kang, J. H.
MOVEMENT DISORDERS, 2023, 38 : S229 - S229

← 1 2 3 4 5 →