Chemistry of Antitumor Renieramycin Marine Natural Products

被引：1

作者：

Yokoya, Masashi ^{[1
]}

Saito, Naoki ^{[1
]}

机构：

[1] Meiji Pharmaceut Univ, Grad Sch Pharmaceut Sci, Tokyo 2048588, Japan

来源：

JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN | 2015年 / 73卷 / 07期

关键词：

renieramycin; antitumor; total synthesis; isolation; isoquinoline alkaloid; marine natural product; STEREOCONTROLLED TOTAL SYNTHESIS; SELENIUM OXIDE OXIDATION; ALPHA-AMINO-ACIDS; ANTINEOPLASTIC AGENTS; STRUCTURE ELUCIDATION; ASYMMETRIC-SYNTHESIS; SAFRAMYCIN-D; ANTIBIOTICS; ISOQUINOLINEQUINONE; DERIVATIVES;

D O I：

10.5059/yukigoseikyokaishi.73.723

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Renieramycin marine natural products have been attracting many synthetic organic chemists and natural product researchers due to their promising biological activities along with unique skeletal characteristics. This paper described our recent synthetic studies on total syntheses of renieramycin G and cribrostatin 4 along with powerful contribution for isolation and structure determination of several stabilized renieramycin derivatives via KCN pretreated Thai blue sponge, Xestospongia sp. Several chemical transformations of natural products also presented.

引用

页码：723 / 736

页数：14

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