Control of viral hepatitis infection in Africa: Are we dreaming?

被引:2
|
作者
Mihigo, Richard [1 ]
Nshimirimana, Deo [1 ]
Hall, Andrew [2 ]
Kew, Michael [3 ]
Wiersma, Steven [4 ]
Clements, C. John [5 ]
机构
[1] World Hlth Org Reg Off Africa, Immunizat & Vaccine Dev Programme, Brazzaville, Rep Congo
[2] London Sch Hyg & Trop Med, London WC1, England
[3] Univ Cape Town, ZA-7700 Rondebosch, South Africa
[4] WHO, Expanded Programme Immunizat, CH-1211 Geneva, Switzerland
[5] Univ Melbourne, Melbourne, Vic, Australia
关键词
Vaccines; Viral hepatitis; Africa; Control; Hepatitis A; Hepatitis B; Hepatitis C; Hepatitis D; Delta hepatitis; Hepatitis E; B-VIRUS; HIV; TRANSMISSION; GHANA; HBV;
D O I
10.1016/j.vaccine.2012.11.001
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Background: At least five different types of viral hepatitis cause problems of significant public health importance in Africa, where together they constitute a huge burden of disease. But until now, efforts to control the infections have been largely piecemeal. Analysis of the strategies needed to control each virus, however, reveals major overlaps. Proposal: We propose that the control of these infections in the WHO African Region should start with the common strategies rather than with each disease. But this approach presents potentially huge problems to overcome, such as the difficulty of integrating multiple health service elements - the track record for successful integration of such services is not good. This is despite encouraging rhetoric from donors and national leaders alike. And to succeed, disparate programmes must work closely together. But we believe that the time is right to create new opportunities for prevention and treatment of hepatitis, including increasing education, and promoting screening and treatment for more than 500 million people already infected with hepatitis B and C viruses. Impact: The impact of these efforts on decreasing mortality and morbidity will be significant because of the high burden of disease from these infections, and also because the effect will spill over to benefit the control of other communicable diseases and health systems strengthening. Such a project will inevitably involve multiple strategies that will vary somewhat according to the epidemiology of the diseases and the location. (C) 2012 Elsevier Ltd. All rights reserved.
引用
收藏
页码:341 / 346
页数:6
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