An integrin-like protein in Candida albicans: Implications for pathogenesis

被引：22
|
作者：
Hostetter, MK [1 ]
机构：
[1] UNIV MINNESOTA,DEPT PEDIAT,MINNEAPOLIS,MN 55455
来源：
TRENDS IN MICROBIOLOGY | 1996年 / 4卷 / 06期
关键词：
D O I：
10.1016/0966-842X(96)10036-6
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Candida albicans is the foremost fungal pathogen in neonates, diabetics and immunocompromised people. The discovery of integrin-like proteins in this yeast and the involvement of these proteins in adhesion, morphogenesis and signal transduction suggest important roles for primitive integrins in the pathogenesis of infectious diseases, and as paradigms for signaling and differentiation in vertebrate cells.
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页码：242 / 246
页数：5
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