Molecules of the plant world are proving their effectiveness in countering, slowing down, and regressing many diseases. The resveratrol for its intrinsic properties related to its stilbene structure has been proven to be a universal panacea, especially for a wide range of neurodegenerative diseases. This paper evaluates (in vivo and in vitro) the various molecular targets of this peculiar polyphenol and its ability to effectively counter several neurodegenerative disorders such as Parkinson's, Alzheimer's, and Huntington's diseases and amyotrophic lateral sclerosis. What emerges is that, in the deep heterogeneity of the pathologies evaluated, resveratrol through a convergence on the protein targets is able to give therapeutic responses in neuronal cells deeply diversified not only in morphological structure but especially in their function performed in the anatomical district to which they belong.
机构:Ouachita Baptist Univ, Dept Biol, Jones Sci Ctr, Arkadelphia, AR 71998 USA
Wight, Randall D.
Tull, Cameron A.
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机构:Ouachita Baptist Univ, Dept Biol, Jones Sci Ctr, Arkadelphia, AR 71998 USA
Tull, Cameron A.
Deel, Matthew W.
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机构:Ouachita Baptist Univ, Dept Biol, Jones Sci Ctr, Arkadelphia, AR 71998 USA
Deel, Matthew W.
Stroope, Brooke L.
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机构:Ouachita Baptist Univ, Dept Biol, Jones Sci Ctr, Arkadelphia, AR 71998 USA
Stroope, Brooke L.
Eubanks, Amy G.
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机构:Ouachita Baptist Univ, Dept Biol, Jones Sci Ctr, Arkadelphia, AR 71998 USA
Eubanks, Amy G.
Chavis, Janet A.
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Univ Arkansas Med Sci, Dept Neurobiol & Dev Sci, Little Rock, AR 72205 USAOuachita Baptist Univ, Dept Biol, Jones Sci Ctr, Arkadelphia, AR 71998 USA
Chavis, Janet A.
Drew, Paul D.
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Univ Arkansas Med Sci, Dept Neurobiol & Dev Sci, Little Rock, AR 72205 USAOuachita Baptist Univ, Dept Biol, Jones Sci Ctr, Arkadelphia, AR 71998 USA
Drew, Paul D.
Hensley, Lori L.
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Ouachita Baptist Univ, Dept Biol, Jones Sci Ctr, Arkadelphia, AR 71998 USAOuachita Baptist Univ, Dept Biol, Jones Sci Ctr, Arkadelphia, AR 71998 USA