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PREDICTIVE SIGNIFICANCE OF A COMPLEX APPROACH IN DETERMINING THE VASCULAR WALL STIFFNESS PARAMETERS IN PATIENTS WITH ARTERIAL HYPERTENSION AND IN PATIENTS WITH ARTERIAL HYPERTENSION AFTER ISCHEMIC STROKE
被引:0
|作者:
Kindaliova, V. G.
[1
]
Pronko, T. P.
[1
]
Dobrodey, M. A.
[1
]
Gubkin, S., V
[2
]
机构:
[1] Grodno State Med Univ, 80 Gorky Str, Grodno 230009, BELARUS
[2] Natl Acad Sci Belarus, Inst Physiol, 28 Akad Skaya Str, Minsk 220072, BELARUS
来源:
DOKLADY NATSIONALNOI AKADEMII NAUK BELARUSI
|
2022年
/
66卷
/
05期
关键词:
arterial stiffness;
prognosis;
arterial hypertension;
ischemic stroke;
RISK;
D O I:
10.29235/1561-8323-2022-66-5-525-532
中图分类号:
O [数理科学和化学];
P [天文学、地球科学];
Q [生物科学];
N [自然科学总论];
学科分类号:
07 ;
0710 ;
09 ;
摘要:
The article presents the information about the predictive significance of a complex approach in determining vascular wall stiffness parameters. A total of 159 people with arterial hypertension (AH) and AH after a previous ischemic stroke were examined. A model with a conditional linear predictor (LP) was constructed, using a binary regression equation with a probit-link function for prediction of cardiovascular events. LP is a combination of indicators such as age (A), glomer-ular filtration rate (CKD-EPI), pulse wave velocity (PWV), intima-media thickness (IMT), cardio-ankle vascular index (CAVI) and augmentation index (AI). The equation has the following form: LP = -6.6139 - 0.0978A + 0.031CKD-EPI + 0.0758PWV + 3.2086IMT + 0.4421CAVI + 1.2429AI. The cut-off threshold for LP = 0.0238, sensitivity (Se) 85.71 %, specificity (Sp) 77 % and accuracy (Acc) 78.07 %.
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页码:525 / 532
页数:8
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