Improved NMR structures of protein/ligand complexes using residual dipolar couplings

被引：32

作者：

Olejniczak, ET ^{[1
]}

Meadows, RP ^{[1
]}

Wang, H ^{[1
]}

Cai, ML ^{[1
]}

Nettesheim, DG ^{[1
]}

Fesik, SW ^{[1
]}

机构：

[1] Abbott Labs, Div Pharmaceut Discovery, Abbott Pk, IL 60064 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1999年 / 121卷 / 39期

关键词：

D O I：

10.1021/ja992139j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：9249 / 9250

页数：2

共 19 条

[1]

[Anonymous], CURR OPIN STRUCT BIO

[2] A HIGH-TEMPERATURE SUPERCONDUCTING RECEIVER FOR NUCLEAR-MAGNETIC-RESONANCE MICROSCOPY [J].

BLACK, RD ;

EARLY, TA ;

ROEMER, PB ;

MUELLER, OM ;

MOGROCAMPERO, A ;

TURNER, LG ;

JOHNSON, GA .

SCIENCE, 1993, 259 (5096) :793-795

[3]

Brunger AT, 1993, XPLOR MANUAL VERSION

[4] Measurement of residual dipolar couplings of macromolecules aligned in the nematic phase of a colloidal suspension of rod-shaped viruses [J].

Clore, GM ;

Starich, MR ;

Gronenborn, AM .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1998, 120 (40) :10571-10572

[5] New methods of structure refinement for macromolecular structure determination by NMR [J].

Clore, GM ;

Gronenborn, AM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (11) :5891-5898

[6] Protein backbone angle restraints from searching a database for chemical shift and sequence homology [J].

Cornilescu, G ;

Delaglio, F ;

Bax, A .

JOURNAL OF BIOMOLECULAR NMR, 1999, 13 (03) :289-302

[7]

Garrett DS, 1999, NAT STRUCT BIOL, V6, P166

[8] APPLICATION OF THE 3-DIMENSIONAL STRUCTURES OF PROTEIN TARGET MOLECULES IN STRUCTURE-BASED DRUG DESIGN [J].

GREER, J ;

ERICKSON, JW ;

BALDWIN, JJ ;

VARNEY, MD .

JOURNAL OF MEDICINAL CHEMISTRY, 1994, 37 (08) :1035-1054

[9] High-throughput nuclear magnetic resonance-based screening [J].

Hajduk, PJ ;

Gerfin, T ;

Boehlen, JM ;

Häberli, M ;

Marek, D ;

Fesik, SW .

JOURNAL OF MEDICINAL CHEMISTRY, 1999, 42 (13) :2315-2317

[10] Tunable alignment of macromolecules by filamentous phage yields dipolar coupling interactions [J].

Hansen, MR ;

Mueller, L ;

Pardi, A .

NATURE STRUCTURAL BIOLOGY, 1998, 5 (12) :1065-1074

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