Lipids at the interface of virus-host interactions

被引:86
|
作者
Chukkapalli, Vineela [1 ]
Heaton, Nicholas S. [1 ]
Randall, Glenn [1 ]
机构
[1] Univ Chicago, Dept Microbiol, Chicago, IL 60637 USA
关键词
HEPATITIS-C VIRUS; FATTY-ACID SYNTHASE; ACTIVATED PROTEIN-KINASE; 4-KINASE III ALPHA; HUMAN CYTOMEGALOVIRUS; RNA REPLICATION; VIRAL REPLICATION; PHOSPHOLIPID BIOSYNTHESIS; ENDOPLASMIC-RETICULUM; GENOME REPLICATION;
D O I
10.1016/j.mib.2012.05.013
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Viruses physically and metabolically remodel the host cell to establish an optimal environment for their replication. Many of these processes involve the manipulation of lipid signaling, synthesis, and metabolism. An emerging theme is that these lipid-modifying pathways are also linked to innate antiviral responses and can be,modulated to inhibit viral replication.
引用
收藏
页码:512 / 518
页数:7
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