HIV-inhibitory natural products .28. Diterpene carboxylic acid from fruits of Xylopia sp

被引：8
|
作者：
Fuller, RW [1 ]
Cardellina, JH [1 ]
Boyd, MR [1 ]
机构：
[1] NCI, FREDERICK CANC RES & DEV CTR, DIV CANC TREATMENT, DEV THERAPEUT PROGRAM, FREDERICK, MD 21702 USA
来源：
NATURAL PRODUCT LETTERS | 1996年 / 8卷 / 03期
关键词：
HIV-inhibitory; kaurane; diterpene acid; Xylopia sp;
D O I：
10.1080/10575639608044890
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A new kaurane diterpene was isolated and identified as the major HIV-inhibitory constituent of the aqueous extract of fruits of a Xylopia sp. plant. Analysis of spectral data revealed the structure of the compound, xylopinic acid (1), a new diastereomer of a compound previously known only as a chemical/microbial transformation product.
引用
收藏
页码：169 / 172
页数：4
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