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- [1] Structure-Activity Relationships and Optimization of 3,5-Dichloropyridine Derivatives As Novel P2X7 Receptor AntagonistsJOURNAL OF MEDICINAL CHEMISTRY, 2012, 55 (08) : 3687 - 3698Lee, Won-Gil论文数: 0 引用数: 0 h-index: 0机构: GIST, Sch Life Sci, Kwangju 500712, South Korea GIST, Sch Life Sci, Kwangju 500712, South KoreaLee, So-Deok论文数: 0 引用数: 0 h-index: 0机构: GIST, Sch Life Sci, Kwangju 500712, South Korea GIST, Sch Life Sci, Kwangju 500712, South KoreaCho, Joong-Heui论文数: 0 引用数: 0 h-index: 0机构: GIST, Sch Life Sci, Kwangju 500712, South Korea GIST, Sch Life Sci, Kwangju 500712, South KoreaJung, Younghwan论文数: 0 引用数: 0 h-index: 0机构: GIST, Sch Life Sci, Kwangju 500712, South Korea GIST, Sch Life Sci, Kwangju 500712, South KoreaKim, Jeong-hyun论文数: 0 引用数: 0 h-index: 0机构: GIST, Sch Life Sci, Kwangju 500712, South Korea GIST, Sch Life Sci, Kwangju 500712, South KoreaHien, Tran T.论文数: 0 引用数: 0 h-index: 0机构: Seoul Natl Univ, Coll Pharm, Seoul, South Korea GIST, Sch Life Sci, Kwangju 500712, South KoreaKang, Keon-Wook论文数: 0 引用数: 0 h-index: 0机构: Seoul Natl Univ, Coll Pharm, Seoul, South Korea GIST, Sch Life Sci, Kwangju 500712, South KoreaKo, Hyojin论文数: 0 引用数: 0 h-index: 0机构: GIST, Grad Program Med Syst Engn, Kwangju 500712, South Korea GIST, Sch Life Sci, Kwangju 500712, South KoreaKim, Yong-Chul论文数: 0 引用数: 0 h-index: 0机构: GIST, Sch Life Sci, Kwangju 500712, South Korea GIST, Grad Program Med Syst Engn, Kwangju 500712, South Korea GIST, Sch Life Sci, Kwangju 500712, South Korea
- [2] Synthesis and structure-activity relationships of pyrazolodiazepine derivatives as human P2X7 receptor antagonistsBIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2009, 19 (21) : 6053 - 6058Lee, Ju-Yeon论文数: 0 引用数: 0 h-index: 0机构: Gwangju Inst Sci & Technol, Res Ctr Biomol Nanotechnol, Dept Life Sci, Kwangju, South Korea Gwangju Inst Sci & Technol, Res Ctr Biomol Nanotechnol, Dept Life Sci, Kwangju, South KoreaYu, Juan论文数: 0 引用数: 0 h-index: 0机构: Gwangju Inst Sci & Technol, Res Ctr Biomol Nanotechnol, Dept Life Sci, Kwangju, South Korea Gwangju Inst Sci & Technol, Res Ctr Biomol Nanotechnol, Dept Life Sci, Kwangju, South KoreaCho, Won Je论文数: 0 引用数: 0 h-index: 0机构: Chonnam Natl Univ, Coll Pharm, Kwangju, South Korea Gwangju Inst Sci & Technol, Res Ctr Biomol Nanotechnol, Dept Life Sci, Kwangju, South KoreaKo, Hyojin论文数: 0 引用数: 0 h-index: 0机构: Gwangju Inst Sci & Technol, Res Ctr Biomol Nanotechnol, Dept Life Sci, Kwangju, South Korea Gwangju Inst Sci & Technol, Grad Program Med Syst Engn, Kwangju, South Korea Gwangju Inst Sci & Technol, Res Ctr Biomol Nanotechnol, Dept Life Sci, Kwangju, South KoreaKim, Yong-Chul论文数: 0 引用数: 0 h-index: 0机构: Gwangju Inst Sci & Technol, Res Ctr Biomol Nanotechnol, Dept Life Sci, Kwangju, South Korea Gwangju Inst Sci & Technol, Grad Program Med Syst Engn, Kwangju, South Korea Gwangju Inst Sci & Technol, Res Ctr Biomol Nanotechnol, Dept Life Sci, Kwangju, South Korea
- [3] Structure-Activity Relationships and Therapeutic Potential of Purinergic P2X7 Receptor AntagonistsCURRENT MEDICINAL CHEMISTRY, 2024, 31 (11) : 1361 - 1403El Idrissi, Imane Ghafir论文数: 0 引用数: 0 h-index: 0机构: Univ Bari Aldo Moro, Dipartimento Farm Sci Farmaco, Via Orabona 4, I-70125 Bari, Italy Univ Bari Aldo Moro, Dipartimento Farm Sci Farmaco, Via Orabona 4, I-70125 Bari, ItalyPodlewska, Sabina论文数: 0 引用数: 0 h-index: 0机构: Polish Acad Sci, Maj Inst Pharmacol, Dept Med Chem, 12 Smetna St, PL-31343 Krakow, Poland Univ Bari Aldo Moro, Dipartimento Farm Sci Farmaco, Via Orabona 4, I-70125 Bari, Italy论文数: 引用数: h-index:机构:Bojarski, Andrzej J.论文数: 0 引用数: 0 h-index: 0机构: Polish Acad Sci, Maj Inst Pharmacol, Dept Med Chem, 12 Smetna St, PL-31343 Krakow, Poland Univ Bari Aldo Moro, Dipartimento Farm Sci Farmaco, Via Orabona 4, I-70125 Bari, ItalyLacivita, Enza论文数: 0 引用数: 0 h-index: 0机构: Univ Bari Aldo Moro, Dipartimento Farm Sci Farmaco, Via Orabona 4, I-70125 Bari, Italy Univ Bari Aldo Moro, Dipartimento Farm Sci Farmaco, Via Orabona 4, I-70125 Bari, Italy论文数: 引用数: h-index:机构:
- [4] Discovery and structure-activity relationships of a series of pyroglutamic acid amide antagonists of the P2X7 receptorBIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2010, 20 (17) : 5080 - 5084Abdi, Muna H.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, EnglandBeswick, Paul J.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, EnglandBillinton, Andy论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, EnglandChambers, Laura J.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, EnglandCharlton, Andrew论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, EnglandCollins, Sue D.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, EnglandCollis, Katharine L.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, EnglandDean, David K.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, EnglandFonfria, Elena论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, EnglandGleave, Robert J.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, EnglandLejeune, Clarisse L.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, EnglandLivermore, David G.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, EnglandMedhurst, Stephen J.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, EnglandMichel, Anton D.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, EnglandMoses, Andrew P.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, EnglandPage, Lee论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, EnglandPatel, Sadhana论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, EnglandRoman, Shilina A.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, EnglandSenger, Stefan论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, EnglandSlingsby, Brian论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, EnglandSteadman, Jon G. A.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, EnglandStevens, Alexander J.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, EnglandWalter, Daryl S.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England
- [5] Novel P2X7 receptor antagonistsBIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2003, 13 (22) : 4043 - 4046Alcaraz, L论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca R&D Charnwood, Dept Med Chem, Loughborough LE11 5RH, Leics, EnglandBaxter, A论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca R&D Charnwood, Dept Med Chem, Loughborough LE11 5RH, Leics, EnglandBent, J论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca R&D Charnwood, Dept Med Chem, Loughborough LE11 5RH, Leics, EnglandBowers, K论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca R&D Charnwood, Dept Med Chem, Loughborough LE11 5RH, Leics, EnglandBraddock, M论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca R&D Charnwood, Dept Med Chem, Loughborough LE11 5RH, Leics, EnglandCladingboel, D论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca R&D Charnwood, Dept Med Chem, Loughborough LE11 5RH, Leics, EnglandDonald, D论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca R&D Charnwood, Dept Med Chem, Loughborough LE11 5RH, Leics, EnglandFagura, M论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca R&D Charnwood, Dept Med Chem, Loughborough LE11 5RH, Leics, EnglandFurber, M论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca R&D Charnwood, Dept Med Chem, Loughborough LE11 5RH, Leics, EnglandLaurent, C论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca R&D Charnwood, Dept Med Chem, Loughborough LE11 5RH, Leics, EnglandLawson, M论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca R&D Charnwood, Dept Med Chem, Loughborough LE11 5RH, Leics, EnglandMortimore, M论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca R&D Charnwood, Dept Med Chem, Loughborough LE11 5RH, Leics, EnglandMcCormick, M论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca R&D Charnwood, Dept Med Chem, Loughborough LE11 5RH, Leics, EnglandRoberts, N论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca R&D Charnwood, Dept Med Chem, Loughborough LE11 5RH, Leics, EnglandRobertson, M论文数: 0 引用数: 0 h-index: 0机构: AstraZeneca R&D Charnwood, Dept Med Chem, Loughborough LE11 5RH, Leics, England
- [6] Structure-activity relationships and in vivo activity of (1H-pyrazol-4-yl)acetamide antagonists of the P2X7 receptorBIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2010, 20 (15) : 4653 - 4656Beswick, Paul J.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, EnglandBillinton, Andy论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, EnglandChambers, Laura J.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, EnglandDean, David K.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, EnglandFonfria, Elena论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, EnglandGleave, Robert J.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, EnglandMedhurst, Stephen J.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, EnglandMichel, Anton D.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, EnglandMoses, Andrew P.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, EnglandPatel, Sadhana论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, EnglandRoman, Shilina A.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, EnglandRoomans, Sue论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, EnglandSenger, Stefan论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, EnglandStevens, Alexander J.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, EnglandWalter, Daryl S.论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England GlaxoSmithKline, Neurosci Ctr Excellence Drug Discovery, Harlow CM19 5AW, Essex, England
- [7] Structure-activity relationship studies of pyrimidine-2,4-dione derivatives as potent P2X7 receptor antagonistsEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 106 : 180 - 193Park, Jin-Hee论文数: 0 引用数: 0 h-index: 0机构: GIST, Sch Life Sci, Gwangju 500712, South Korea GIST, Sch Life Sci, Gwangju 500712, South KoreaLee, Ga-Eun论文数: 0 引用数: 0 h-index: 0机构: KHIDI, Dept Pharmaceut Ind, Chungcheorigbuk Do 363700, South Korea GIST, Sch Life Sci, Gwangju 500712, South KoreaLee, So-Deok论文数: 0 引用数: 0 h-index: 0机构: GIST, Sch Life Sci, Gwangju 500712, South Korea GIST, Sch Life Sci, Gwangju 500712, South KoreaKo, Hyojin论文数: 0 引用数: 0 h-index: 0机构: GIST, Sch Life Sci, Gwangju 500712, South Korea GIST, Sch Life Sci, Gwangju 500712, South KoreaKim, Yong-Chul论文数: 0 引用数: 0 h-index: 0机构: GIST, Sch Life Sci, Gwangju 500712, South Korea GIST, Dept Med Syst Enginerring, Gwangju 500712, South Korea GIST, Sch Life Sci, Gwangju 500712, South Korea
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