Disruption of the Autophagy-Regulatory Becn1-Bcl2 Complex Impairs Insulin Storage and Secretion in Mice

被引：1
|
作者：
Yamamoto, Soh
Wang, Nan
Zhang, Weiran
He, Congcong
机构：
来源：
DIABETES | 2018年 / 67卷
关键词：
D O I：
10.2337/db18-2432-PUB
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页数：2
相关论文
共 13 条
  • [1] The BECN1-BCL2 complex regulates insulin secretion and storage in mice
    Kuramoto, Kenta
    He, Congcong
    AUTOPHAGY, 2018, 14 (11) : 2026 - 2028
  • [2] Disruption of the beclin 1–BCL2 autophagy regulatory complex promotes longevity in mice
    Álvaro F. Fernández
    Salwa Sebti
    Yongjie Wei
    Zhongju Zou
    Mingjun Shi
    Kathryn L. McMillan
    Congcong He
    Tabitha Ting
    Yang Liu
    Wei-Chung Chiang
    Denise K. Marciano
    Gabriele G. Schiattarella
    Govind Bhagat
    Orson W. Moe
    Ming Chang Hu
    Beth Levine
    Nature, 2018, 558 : 136 - 140
  • [3] Disruption of the beclin 1-BCL2 autophagy regulatory complex promotes longevity in mice
    Fernandez, Alvaro F.
    Sebti, Salwa
    Wei, Yongjie
    Zou, Zhongju
    Shi, Mingjun
    Mcmillan, Kathryn L.
    He, Congcong
    Ting, Tabitha
    Liu, Yang
    Chiang, Wei-Chung
    Marciano, Denise K.
    Schiattarella, Gabriele G.
    Bhagat, Govind
    Moe, Orson W.
    Hu, Ming Chang
    Levine, Beth
    NATURE, 2018, 558 (7708) : 136 - +
  • [4] Author Correction: Disruption of the beclin 1–BCL2 autophagy regulatory complex promotes longevity in mice
    Álvaro F. Fernández
    Salwa Sebti
    Yongjie Wei
    Zhongju Zou
    Mingjun Shi
    Kathryn L. McMillan
    Congcong He
    Tabitha Ting
    Yang Liu
    Wei-Chung Chiang
    Denise K. Marciano
    Gabriele G. Schiattarella
    Govind Bhagat
    Orson W. Moe
    Ming Chang Hu
    Beth Levine
    Nature, 2018, 561 : E30 - E30
  • [5] Disruption of the beclin 1-BCL2 autophagy regulatory complex promotes longevity in mice (vol 558, pg 136, 2018)
    Fernandez, Alvaro F.
    Sebti, Salwa
    Wei, Yongjie
    Zou, Zhongju
    Shi, Mingjun
    McMillan, Kathryn L.
    He, Congcong
    Ting, Tabitha
    Liu, Yang
    Chiang, Wei-Chung
    Marciano, Denise K.
    Schiattarella, Gabriele G.
    Bhagat, Govind
    Moe, Orson W.
    Hu, Ming Chang
    Levine, Beth
    NATURE, 2018, 561 (7723) : E30 - E30
  • [6] BAX and BAK1 are dispensable for ABT-737-induced dissociation of the BCL2-BECN1 complex and autophagy
    Bravo-San Pedro, Jose Manuel
    Wei, Yongjie
    Sica, Valentina
    Maiuri, Maria Chiara
    Zou, Zhongju
    Kroemer, Guido
    Levine, Beth
    AUTOPHAGY, 2015, 11 (03) : 452 - 459
  • [7] MYBL2 guides autophagy suppressor VDAC2 in the developing ovary to inhibit autophagy through a complex of VDAC2-BECN1-BCL2L1 in mammals
    Yuan, Jia
    Zhang, Ying
    Sheng, Yue
    Fu, Xiazhou
    Cheng, Hanhua
    Zhou, Rongjia
    AUTOPHAGY, 2015, 11 (07) : 1081 - 1098
  • [8] Disruption of beta cell acetyl-CoA carboxylase-1 in mice impairs insulin secretion and beta cell mass
    Cantley, James
    Davenport, Aimee
    Vetterli, Laurene
    Nemes, Nandor J.
    Whitworth, P. Tess
    Boslem, Ebru
    Thai, Le May
    Mellett, Natalie
    Meikle, Peter J.
    Hoehn, Kyle L.
    James, David E.
    Biden, Trevor J.
    DIABETOLOGIA, 2019, 62 (01) : 99 - 111
  • [9] Disruption of beta cell acetyl-CoA carboxylase-1 in mice impairs insulin secretion and beta cell mass
    James Cantley
    Aimee Davenport
    Laurène Vetterli
    Nandor J. Nemes
    P. Tess Whitworth
    Ebru Boslem
    Le May Thai
    Natalie Mellett
    Peter J. Meikle
    Kyle L. Hoehn
    David E. James
    Trevor J. Biden
    Diabetologia, 2019, 62 : 99 - 111
  • [10] Targeted disruption of the IA-2β gene causes glucose intolerance and impairs insulin secretion but does not prevent the development of diabetes in NOD mice
    Kubosaki, A
    Gross, S
    Miura, J
    Saeki, K
    Zhu, M
    Nakamura, S
    Hendriks, W
    Notkins, AL
    DIABETES, 2004, 53 (07) : 1684 - 1691
12