RNAi-Based Functional Genomics Screening of the Human Kinome Identifies Major Growth Regulating Kinases in Acute Myeloid Leukemia Cells

被引:0
|
作者
Tibes, Raoul [1 ]
Choudhary, Ashish [1 ]
Henrichs, Amanda [1 ]
Guled, Sadia [1 ]
Monzon, Irma [1 ]
Peralta, Lourdes [1 ]
Kiefer, Jeff [1 ]
Azorsa, David [1 ]
机构
[1] Translat Genom Res Inst TGen, Pharmaceut Genom Div, TGen Clin Res Serv, Scottsdale, AZ USA
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:1014 / 1014
页数:1
相关论文
共 50 条
  • [1] RNAi functional screening of the tyrosine kinome identifies therapeutic targets in acute myeloid leukemia patients
    Tyner, Jeffrey W.
    Willis, Stephanie
    Deininger, Michael W. N.
    Druker, Brian J.
    BLOOD, 2007, 110 (11) : 69A - 69A
  • [2] RNAi screening of the tyrosine kinome identifies therapeutic targets in acute myeloid leukemia
    Tyner, Jeffrey W.
    Walters, Denise K.
    Willis, Stephanie G.
    Luttropp, Mary
    Oost, Jason
    Loriaux, Marc
    Erickson, Heidi
    Corbin, Amie S.
    O'Hare, Thomas
    Heinrich, Michael C.
    Deininger, Michael W.
    Druker, Brian J.
    BLOOD, 2008, 111 (04) : 2238 - 2245
  • [3] Identification of Sensitizing Targets to the Hypomethylating Agent 5-Azacytidine in Acute Myeloid Leukemia Cells Using RNAi-Based Functional Genomics Screening.
    Tibes, Raoul
    Choudhary, Ashish
    Henrichs, Amanda
    Guled, Sadia
    Monzon, Irma
    Peralta, Lourdes
    Mousses, Spyro
    Azorsa, David
    BLOOD, 2008, 112 (11) : 921 - 921
  • [4] RNAi-based screening of the human kinome identifies Akt-cooperating kinases: a new approach to designing efficacious multitargeted kinase inhibitors
    S Morgan-Lappe
    K W Woods
    Q Li
    M G Anderson
    M E Schurdak
    Y Luo
    V L Giranda
    S W Fesik
    J D Leverson
    Oncogene, 2006, 25 : 1340 - 1348
  • [5] RNAi-Based Functional Genomics Identifies New Virulence Determinants in Mucormycosis
    Trung Anh Trieu
    Isabel Navarro-Mendoza, Maria
    Perez-Arques, Carlos
    Sanchis, Marta
    Capilla, Javier
    Navarro-Rodriguez, Patricia
    Lopez-Fernandez, Loida
    Torres-Martinez, Santiago
    Garre, Victoriano
    Maria Ruiz-Vazquez, Rosa
    Nicolas, Francisco E.
    PLOS PATHOGENS, 2017, 13 (01)
  • [6] RNAi-based screening of the human kinome identies Akt-cooperating kinases: a new approach to designing efficacious multitargeted kinase inhibitors
    Morgan-Lappe, S
    Woods, KW
    Li, Q
    Anderson, MG
    Schurdak, ME
    Luo, Y
    Giranda, VL
    Fesik, SW
    Leverson, JD
    ONCOGENE, 2006, 25 (09) : 1340 - 1348
  • [7] Genome-wide RNAi-based functional genomics identifies novel genes and pathways that regulate melanoma chemoresistance
    Aruri, J.
    Ho, H.
    White, M. A.
    Ganesan, A. K.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2009, 129 : S139 - S139
  • [8] In Vivo RNAi Screening Identifies HDAC4 As a Mediator Of Chemoresistance In Acute Myeloid Leukemia
    Lettermann, Stephanie
    Agelopoulos, Konstantin
    Rohde, Christian
    Lindtner, Beate
    Marek, Linda
    Hempel, Georg
    Stelljes, Matthias
    Berdel, Wolfgang E.
    Kurz, Thomas
    Mueller-Tidow, Carsten
    BLOOD, 2013, 122 (21)
  • [9] Integrated RNAi screening identifies the NEDDylation pathway as a synergistic partner of azacytidine in acute myeloid leukemia
    Justine Klosner
    Konstantin Agelopoulos
    Christian Rohde
    Stefanie Göllner
    Christoph Schliemann
    Wolfgang E. Berdel
    Carsten Müller-Tidow
    Scientific Reports, 11
  • [10] GC/MS characterization and computational kinome-wide screening of pomegranate fruit extract identifies key phytochemicals interacting to CDK kinases implicated in acute myeloid leukemia cells
    Abohassan, Mohammad
    Al Shahrani, Mesfer
    Ahmad, Irfan
    Abullais, Shahabe Saquib
    Srivastava, Saurabh
    Rajagopalan, Prasanna
    JOURNAL OF FOOD BIOCHEMISTRY, 2022, 46 (08)