Notch signaling can be up-regulated through modification of presenilin/γ-secretase-mediated S3 cleavage

被引:0
|
作者
Tagami, Shinji [1 ]
Okochi, Masayasu [1 ]
Takeda, Masatoshi [1 ]
机构
[1] Osaka Univ, Grad Sch Med, Suita, Osaka 565, Japan
关键词
D O I
暂无
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
引用
收藏
页码:S67 / S67
页数:1
相关论文
共 14 条
  • [1] AIBP Limits Angiogenesis Through γ-Secretase-Mediated Upregulation of Notch Signaling
    Mao, Renfang
    Meng, Shu
    Gu, Qilin
    Araujo-Gutierrez, Raquel
    Kumar, Sandeep
    Yan, Qing
    Almazan, Felicidad
    Youker, Keith A.
    Fu, Yingbin
    Pownall, Henry J.
    Cooke, John P.
    Miller, Yury I.
    Fang, Longhou
    CIRCULATION RESEARCH, 2017, 120 (11) : 1727 - +
  • [2] Calsenilin regulates presenilin 1/γ-secretase-mediated N-cadherin ε-cleavage and β-catenin signaling
    Jang, Changhwan
    Choi, Jin-Kyu
    Na, Yeo-Jung
    Jang, Byungki
    Wasco, Wilma
    Buxbaum, Joseph D.
    Kim, Yong-Sun
    Choi, Eun-Kyoung
    FASEB JOURNAL, 2011, 25 (12): : 4174 - 4183
  • [3] Presenilin dependent γ-secretase processing of β-amyloid precursor protein at a site corresponding to the S3 cleavage of Notch
    Sastre, M
    Steiner, H
    Fuchs, K
    Capell, A
    Multhaup, G
    Condron, MM
    Teplow, DB
    Haass, C
    EMBO REPORTS, 2001, 2 (09) : 835 - 841
  • [4] Presenilin dependent γ-secretase processing of β-amyloid precursor protein at a site corresponding to the S3 cleavage of notch
    Steiner, H
    Sastre, M
    Multhaup, G
    Teplow, DB
    Haass, C
    MAPPING THE PROGRESS OF ALZHEIMER'S AND PARKINSON'S DISEASE, 2002, 51 : 91 - 94
  • [5] Regulation of Notch signaling by a novel S3 cleavage diversity
    Tagami, Shinji
    Okochi, Masayasu
    Yanagida, Kanta
    Ikuta, Akiko
    Fukumori, Akio
    Jingwei, Jiang
    Mori, Kohji
    Oguri, Takafumi
    Nishitomi, Kouhei
    Nakayama, Taisuke
    Takeda, Masatoshi
    PSYCHIATRY AND CLINICAL NEUROSCIENCES, 2008, 62 (01) : S7 - S8
  • [6] Regulation of Notch signaling by dynamic changes in the precision of S3 cleavage of Notch-1
    Tagami, Shinji
    Okochi, Masayasu
    Yanagida, Kanta
    Ikuta, Akiko
    Fukumori, Akio
    Matsumoto, Naohiko
    Ishizuka-Katsura, Yoshiko
    Nakayama, Taisuke
    Itoh, Naohiro
    Jiang, Jingwei
    Nishitomi, Kouhei
    Kamino, Kouzin
    Morihara, Takashi
    Hashimoto, Ryota
    Tanaka, Toshihisa
    Kudo, Takashi
    Chiba, Shigeru
    Takeda, Masatoshi
    MOLECULAR AND CELLULAR BIOLOGY, 2008, 28 (01) : 165 - 176
  • [7] Presenilin 1 mutations activate γ42-secretase but reciprocally inhibit ε-secretase cleavage of amyloid precursor protein (APP) and S3-cleavage of Notch
    Chen, FS
    Gu, YJ
    Hasegawa, H
    Ruan, XY
    Arawaka, S
    Fraser, P
    Westaway, D
    Mount, H
    St George-Hyslop, P
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (39) : 36521 - 36526
  • [8] Caveolin-3 upregulation activates β-secretase-mediated cleavage of the amyloid precursor protein in Alzheimer's disease
    Nishiyama, K
    Trapp, BD
    Ikezu, T
    Ransohoff, RM
    Tomita, T
    Iwatsubo, T
    Kanazawa, I
    Hsiao, KK
    Lisanti, MP
    Okamoto, T
    JOURNAL OF NEUROSCIENCE, 1999, 19 (15): : 6538 - 6548
  • [9] Platelet-derived growth factor induces the β-γ-secretase-mediated cleavage of Alzheimer's amyloid precursor protein through a Src-Rac-dependent pathway
    Gianni, D
    Zambrano, N
    Bimonte, M
    Minopoli, G
    Mercken, L
    Talamo, F
    Scaloni, A
    Russo, T
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (11) : 9290 - 9297
  • [10] Signaling through up-regulated C3a receptor is key to the development of experimental lupus nephritis
    Bao, LH
    Osawe, I
    Haas, M
    Quigg, RJ
    JOURNAL OF IMMUNOLOGY, 2005, 175 (03): : 1947 - 1955