Synthesis and application of novel H2O2 fluorescent probe based on the deprotection mechanism

被引：0

作者：

Wu, ZY ^{[1
]}

Fan, ZH ^{[1
]}

Tang, YY ^{[1
]}

Shen, GL ^{[1
]}

Yu, RQ ^{[1
]}

机构：

[1] Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemobiosensing & Chemometr, Changsha 410082, Peoples R China

来源：

ACTA CHIMICA SINICA | 2006年 / 64卷 / 08期

关键词：

3; 6; '-bis(tetramethylethylenedioxyboryl)fluorane; fluorescent probe; H2O2; deprotection;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The compound, 3',6'-bis(tetramethylethylenedioxyboryl)fluorane, synthesized in this experiment is a kind of H2O2 fluorescence-strengthened reagent, which depends on deprotection mechanism and can examine the H2O2 concentration sensitively. The structure of the compound was confirmed by the IR and H-1 NMR spectra. The influences of reaction time, solvent and base on the probe synthesis were investigated in detail. The response time of the fluorescent probe was also studied and as a result, the optimal time for the H2O2 detection is 3 min. The fluorescence intensity of the probe was gradually increased with the increase of H2O2 concentration in the range of 2.3x10(-12)similar to 2.0x10(-8) mol/L, the detection limit of H2O2 was 2.3x10(-12) mol/L, and the recovery rates in the blood serum were in the range of 93.9%similar to 102.2%.

引用

页码：738 / 742

页数：5

共 15 条

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