Separation and purification of 99mTc from 99Mo produced by electron linear accelerator

被引:16
|
作者
Sekimoto, Shun [1 ]
Tatenuma, Katsuyoshi [2 ]
Suzuki, Yumi [2 ]
Tsuguchi, Akira [2 ]
Tanaka, Atsushi [2 ]
Tadokoro, Takahiro [3 ]
Kani, Yuko [3 ]
Morikawa, Yasumasa [4 ]
Yamamoto, Asaki [4 ]
Ohtsuki, Tsutomu [1 ]
机构
[1] Kyoto Univ, Inst Res Reactor, 2-1010 Asashiro Nishi, Osaka 5900494, Japan
[2] Kaken Inc, 1044 Hori Machi, Mito, Ibaraki 3100903, Japan
[3] Hitachi Ltd, Energy & Environm Syst Lab, 7-2-1 Omika, Hitachi, Ibaraki 3191221, Japan
[4] FUJIFILM RI Pharma Co Ltd, 453-1 Shimo Okura,Matsuo Machi, Chiba 2891592, Japan
关键词
Molybdenum-99; Technetium-99m; Technetium master milker; Bremsstrahlung photon; Electron linear accelerator; MO-100(GAMMA;
D O I
10.1007/s10967-016-4959-2
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
The medical radionuclide Mo-99 was produced by the Mo-100(gamma,n) reaction using bremsstrahlung photons generated by an electron linear accelerator. The amount of Mo-99 produced was compared to that predicted by calculation using the particles and heavy ion transport code system. From the Mo-99 produced, highly pure Tc-99m was separated using the so-called technetium master milker, and the chemical yield of Tc-99m was 83-99 %. The installation of a new complex using this method and the electron linear accelerator with the preferable specification was suggested, and a possibility to supply the demand of Tc-99m was discussed and shown.
引用
收藏
页码:1361 / 1366
页数:6
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