Copper(I)-Catalyzed N-Arylation of N1,N3-Dibenzylmalonamide and N1,N3-Dibutylmalonamide Followed by Cleavage of the Malonyl Group with Aryl Halides Under Ligand-Free Conditions

被引：2

作者：

Zheng, W. J. ^{[1
]}

Xu, W. F. ^{[1
]}

Shi, C. X. ^{[2
]}

Ren, F. B. ^{[1
,3
]}

Lu, X. L. ^{[1
]}

Zhou, Y. F. ^{[1
,3
]}

机构：

[1] China Jiliang Univ, Coll Life Sci, Zhejiang Prov Key Lab Biometrol & Inspect & Quara, Hangzhou 310018, Zhejiang, Peoples R China

[2] Shanghai Univ, Sch Environm & Chem Engn, Shanghai 200444, Peoples R China

[3] Zhejiang Apeloa Med Technol Co Ltd, Dongyang 322118, Peoples R China

来源：

ASIAN JOURNAL OF CHEMISTRY | 2013年 / 25卷 / 02期

关键词：

Copper; Cleavage; Cross-coupling; N-1; N-3-Dibenzylmalonamide; N-3-Ditutylmalonamide; CROSS-COUPLING REACTIONS; CATALYZED AMINATION; AROMATIC AMINATION; ALIPHATIC-AMINES; C-C; COPPER; PALLADIUM; IODIDES; BROMIDES; BOND;

D O I：

10.14233/ajchem.2013.13614

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We primarily developed a practical and convenient protocol to synthesize of aromatic amines based on CuI-catalyzed N-arylation of N-1,N-3-dibenzylmalonamide and N-1,N-3-dibutylmalonamide followed by cleavage of the malonyl group with aryl halides under ligand-free conditions giving good yields.

引用

页码：1117 / 1122

页数：6

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