The p53 Reactivating Drug PRIMA-1Met Induces Apoptosis Of Myeloma Cells Via ROS Production

被引：0
|
作者：
Tessoulin, Benoit
Descamps, Geraldine
Godon, Catherine
Bene, Marie C.
Moreau, Philippe
Le Gouill, Steven
Amiot, Martine
Pellat-Deceunynck, Catherine
机构：
来源：
BLOOD | 2013年 / 122卷 / 21期
关键词：
D O I：
10.1182/blood.V122.21.131.131
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
131
引用
收藏
页数：1
相关论文
共 50 条
  • [1] PRIMA-1Met induces myeloma cell death independent of p53 by impairing the GSH/ROS balance
    Tessoulin, Benoit
    Descamps, Geraldine
    Moreau, Philippe
    Maiga, Sophie
    Lode, Laurence
    Godon, Catherine
    Marionneau-Lambot, Severine
    Oullier, Thibauld
    Le Gouill, Steven
    Amiot, Martine
    Pellat-Deceunynck, Catherine
    BLOOD, 2014, 124 (10) : 1626 - 1636
  • [2] PRIMA-1Met induces apoptosis in Waldenstrom's Macroglobulinemia cells independent of p53
    Sobhani, Mona
    Abdi, Jahangir
    Manujendra, Saha N.
    Chen, Christine
    Chang, Hong
    CANCER BIOLOGY & THERAPY, 2015, 16 (05) : 799 - 806
  • [3] Mutant p53 reactivation by PRIMA-1MET induces multiple signaling pathways converging on apoptosis
    J M R Lambert
    A Moshfegh
    P Hainaut
    K G Wiman
    V J N Bykov
    Oncogene, 2010, 29 : 1329 - 1338
  • [4] Mutant p53 reactivation by PRIMA-1MET induces multiple signaling pathways converging on apoptosis
    Lambert, J. M. R.
    Moshfegh, A.
    Hainaut, P.
    Wiman, K. G.
    Bykov, V. J. N.
    ONCOGENE, 2010, 29 (09) : 1329 - 1338
  • [5] Targeting Oxidative Stress With Auranofin or Prima-1Met to Circumvent p53 or Bax/Bak Deficiency in Myeloma Cells
    Tessoulin, Benoit
    Descamps, Geraldine
    Dousset, Christelle
    Amiot, Martine
    Pellat-Deceunynck, Catherine
    FRONTIERS IN ONCOLOGY, 2019, 9
  • [6] The p53 reactivator PRIMA-1MET synergises with 5-fluorouracil to induce apoptosis in pancreatic cancer cells
    Mohammed, Ibtehal
    Alhammer, Ali Haider
    Arif, Inam Sameh
    INVESTIGATIONAL NEW DRUGS, 2023, 41 (04) : 587 - 595
  • [7] The p53 reactivator PRIMA-1MET synergises with 5-fluorouracil to induce apoptosis in pancreatic cancer cells
    Ibtehal Mohammed
    Ali Haider Alhammer
    Inam Sameh Arif
    Investigational New Drugs, 2023, 41 : 587 - 595
  • [8] PRIMA-1MET induces death in soft-tissue sarcomas cell independent of p53
    Grellety, Thomas
    Laroche-Clary, Audrey
    Chaire, Vanessa
    Lagarde, Pauline
    Chibon, Frederic
    Neuville, Agnes
    Italiano, Antoine
    BMC CANCER, 2015, 15
  • [9] PRIMA-1MET induces death in soft-tissue sarcomas cell independent of p53
    Thomas Grellety
    Audrey Laroche-Clary
    Vanessa Chaire
    Pauline Lagarde
    Frédéric Chibon
    Agnes Neuville
    Antoine Italiano
    BMC Cancer, 15
  • [10] p53-Independent Anti-Myeloma Activity of Prima-1met
    Saha, Manujendra N.
    Jiang, Hua
    Chen Mei-Hsi
    Chang, Hong
    BLOOD, 2011, 118 (21) : 796 - 797
12345