Asymmetric allylic alkylation catalyzed by palladium complexes with new chiral ligands

被引：43
|
作者：
Zhu, GX [1 ]
Terry, M [1 ]
Zhang, XM [1 ]
机构：
[1] PENN STATE UNIV,DEPT CHEM,UNIVERSITY PK,PA 16802
来源：
TETRAHEDRON LETTERS | 1996年 / 37卷 / 26期
关键词：
D O I：
10.1016/0040-4039(96)00905-7
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A potential chiral tridentate ligand based on 2,6-disubstituted pyridine has been prepared and its palladium complexes have been used in asymmetric allylic alkylation. Up to 75 % ee is achieved in the reaction between 1,3-diphenyl-2-propenyl acetate and dimethyl malonate. A control experiment with a similar ligand without pyridine suggests that the bidentate diphosphine coordination is responsible for the asymmetric reaction with this potential tridentate ligand. Copyright (C) 1996 Elsevier Science Ltd
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收藏
页码：4475 / 4478
页数：4
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