The Sirt1 Activator, SRT1720, Attenuates Cardiac Hypertrophy and Fibrosis in a Rodent Pressure Overload Model

被引：0
|
作者：
Ford, Christopher M.
Civitarese, Robert A.
Bugyei-Twum, Antoinette
Mitchell, Melissa
Desjardins, Jean-Francois
Thai, Kern
Abadeh, Armin
Zhang, Yanling
Switzer, Jennifer
Advani, Andrew
Gilbert, Richard E.
Connelly, Kim A.
机构：
来源：
CIRCULATION | 2014年 / 130卷
关键词：
Hypertension; Heart failure; Hemodynamics; Hypertrophy; Heart disease;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
19029
引用
收藏
页数：4
相关论文
共 50 条
  • [1] The Sirt1 activator, SRT1720, attenuates renal fibrosis by inhibiting CTGF and oxidative stress
    Ren, Yunzhuo
    Du, Chunyang
    Shi, Yonghong
    Wei, Jingying
    Wu, Haijiang
    Cui, Huixian
    INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2017, 39 (05) : 1317 - 1324
  • [2] INTRAPERITONEAL INJECTION OF THE SIRT1 ACTIVATOR SRT1720 ATTENUATES THE PROGRESSION OF EXPERIMENTAL OSTEOARTHRITIS IN MICE
    Nishida, K.
    Matsushita, T.
    Takayama, K.
    Nagai, K.
    Tanaka, T.
    Inokuchi, T.
    Kirizuki, S.
    Araki, D.
    Matsumoto, T.
    Kurosaka, M.
    Kuroda, R.
    OSTEOARTHRITIS AND CARTILAGE, 2016, 24 : S359 - S360
  • [3] Intraperitoneal injection of the SIRT1 activator SRT1720 attenuates the progression of experimental osteoarthritis in mice
    Nishida, K.
    Matsushita, T.
    Takayama, K.
    Tanaka, T.
    Miyaji, N.
    Ibaraki, K.
    Araki, D.
    Kanzaki, N.
    Matsumoto, T.
    Kuroda, R.
    BONE & JOINT RESEARCH, 2018, 7 (03): : 252 - 262
  • [4] Search for a novel SIRT1 activator: Structural modification of SRT1720 and biological evaluation
    Matsuya, Yuji
    Kobayashi, Yuta
    Uchida, Sayumi
    Itoh, Yukihiro
    Sawada, Hideyuki
    Suzuki, Takayoshi
    Miyata, Naoki
    Sugimoto, Kenji
    Toyooka, Naoki
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 23 (17) : 4907 - 4910
  • [5] SRT1720, SRT2183, SRT1460, and Resveratrol Are Not Direct Activators of SIRT1
    Pacholec, Michelle
    Bleasdale, John E.
    Chrunyk, Boris
    Cunningham, David
    Flynn, Declan
    Garofalo, Robert S.
    Griffith, David
    Griffor, Matt
    Loulakis, Pat
    Pabst, Brandon
    Qiu, Xiayang
    Stockman, Brian
    Thanabal, Venkataraman
    Varghese, Alison
    Ward, Jessica
    Withka, Jane
    Ahn, Kay
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2010, 285 (11) : 8340 - 8351
  • [6] The SIRT1 Activator SRT1720 Extends Lifespan and Improves Health of Mice Fed a Standard Diet
    Mitchell, Sarah J.
    Martin-Montalvo, Alejandro
    Mercken, Evi M.
    Palacios, Hector H.
    Ward, Theresa M.
    Abulwerdi, Gelareh
    Minor, Robin K.
    Vlasuk, George P.
    Ellis, James L.
    Sinclair, David A.
    Dawson, John
    Allison, David B.
    Zhang, Yongqing
    Becker, Kevin G.
    Bernier, Michel
    de Cabo, Rafael
    CELL REPORTS, 2014, 6 (05): : 836 - 843
  • [7] SRT1720 as an SIRT1 activator for alleviating paraquat-induced models of Parkinson's disease
    Chao, Chih-Chang
    Huang, Chuen-Lin
    Cheng, Jing-Jy
    Chiou, Chun-Tang
    Lee, I-Jung
    Yang, Ying-Chen
    Hsu, Ting-Huang
    Yei, Chia-En
    Lin, Pei-Ying
    Chen, Jih-Jung
    Huang, Nai-Kuei
    REDOX BIOLOGY, 2022, 58
  • [8] The Sirt1 Agonist SRT1720 Increases Mitochondrial Function in Old Rats
    Lanza, Ian R.
    Li, Eileena J.
    Ali, Bushra
    Jakaitis, Daniel R.
    Novak, Colleen M.
    Nair, K. Sreekumaran
    DIABETES, 2009, 58 : A394 - A394
  • [9] SRT1720, a SIRT1 activator, promotes tumor cell migration, and lung metastasis of breast cancer in mice
    Suzuki, Kensuke
    Hayashi, Ryuji
    Ichikawa, Tomomi
    Imanishi, Shingo
    Yamada, Toru
    Inomata, Minehiko
    Miwa, Toshiro
    Matsui, Shoko
    Usui, Isao
    Urakaze, Masaharu
    Matsuya, Yuji
    Ogawa, Hirofumi
    Sakurai, Hiroaki
    Saiki, Ikuo
    Tobe, Kazuyuki
    ONCOLOGY REPORTS, 2012, 27 (06) : 1726 - 1732
  • [10] SRT1720, a sirtuin 1 activator, attenuates organ injury and inflammation in sepsis
    Khader, Adam
    Yang, Weng-Lang
    Hansen, Laura W.
    Rajayer, Salil R.
    Prince, Jose M.
    Nicastro, Jeffrey M.
    Coppa, Gene F.
    Wang, Ping
    JOURNAL OF SURGICAL RESEARCH, 2017, 219 : 288 - 295
12345