Using a combination of chemical and systems biological approaches for defining a mechanism by which a novel anti-aging compound greatly extends yeast longevity

被引:0
|
作者
Titorenko, Vladimir [1 ]
Goldberg, Alexander [1 ]
Bourque, Simon [1 ]
Beach, Adam [1 ]
Burstein, Michelle [1 ]
Richard, Vincent [1 ]
Kyryakov, Pavlo [1 ]
Gregg, Christopher [1 ]
Boukh-Viner, Tatiana [1 ]
Juneau, Mylene [1 ]
Glebova, Anastasia [1 ]
机构
[1] Concordia Univ, Dept Biol, Montreal, PQ H3G 1M8, Canada
来源
FASEB JOURNAL | 2010年 / 24卷
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页数:1
相关论文
共 4 条
  • [1] A novel anti-aging compound extends longevity by remodeling neutral lipid metabolism
    Titorenko, Vladimir
    Beach, Adam
    Richard, Vincent
    Burstein, Michelle
    FASEB JOURNAL, 2012, 26
  • [2] A novel anti-aging compound extends longevity by altering the age-related dynamics of reactive oxygen species
    Titorenko, Vladimir
    Goldberg, Alexander
    Kyryakov, Pavlo
    Bourque, Simon
    Beach, Adam
    Burstein, Michelle
    Richard, Vincent
    FASEB JOURNAL, 2011, 25
  • [3] Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processes
    Goldberg, Alexander A.
    Richard, Vincent R.
    Kyryakov, Pavlo
    Bourque, Simon D.
    Beach, Adam
    Burstein, Michelle T.
    Glebov, Anastasia
    Koupaki, Olivia
    Boukh-Viner, Tatiana
    Gregg, Christopher
    Juneau, Mylene
    English, Ann M.
    Thomas, David Y.
    Titorenko, Vladimir I.
    AGING-US, 2010, 2 (07): : 393 - 414
  • [4] Novel anti-aging small molecules greatly extend yeast life span by specifically targeting a mechanism underlying the essential role of cellular lipid movement and compartmentalized metabolism in regulating longevity
    Titorenko, Vladimir
    Goldberg, Alexander
    Bourque, Simon
    Beach, Adam
    Burstein, Michelle
    Richard, Vincent
    Kyryakov, Pavlo
    Gregg, Christopher
    Boukh-Viner, Tatiana
    Juneau, Mylene
    FASEB JOURNAL, 2010, 24