Bromelain inhibits SARS-CoV-2 infection via targeting ACE-2, TMPRSS2, and spike protein

被引：18
|
作者：
Sagar, Satish [1 ]
Rathinavel, Ashok Kumar [1 ]
Lutz, William E. [1 ]
Struble, Lucas R. [1 ]
Khurana, Surender [2 ]
Schnaubelt, Andy T. [3 ]
Mishra, Nitish Kumar [4 ]
Guda, Chittibabu [4 ,5 ]
Palermo, Nicholas Y. [6 ]
Broadhurst, Mara J. [3 ]
Hoffmann, Tobias [7 ]
Bayles, Kenneth W. [3 ]
Reid, St. Patrick M. [3 ]
Borgstahl, Gloria E. O. [7 ]
Radhakrishnan, Prakash [3 ]
机构：
[1] Univ Nebraska Med Ctr, Eppley Inst Res Canc & Allied Dis, Omaha, NE 68198 USA
[2] US FDA, Ctr Biol Evaluat & Res CBER, Div Viral Prod, Silver Spring, MD USA
[3] Univ Nebraska Med Ctr, Dept Pathol & Microbiol, Omaha, NE 68198 USA
[4] Univ Nebraska Med Ctr, Dept Genet Cell Biol & Anat, Omaha, NE USA
[5] Univ Nebraska Med Ctr, Fred & Pamela Buffett Canc Ctr, Omaha, NE USA
[6] Univ Nebraska Med Ctr, Computat Chem Core, Omaha, NE USA
[7] Robert Koch Inst, Adv Light & Electron Microscopy, Ctr Biol Threats & Special Pathogens 4 ZBS 4, Berlin, Germany
来源：
CLINICAL AND TRANSLATIONAL MEDICINE | 2021年 / 11卷 / 02期
关键词：
D O I：
10.1002/ctm2.281
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页数：6
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