PD-L1-targeted ISAC combines myeloid cell activation, immune-checkpoint inhibition and ADCP to improve anti-tumor efficacy over anti-PD-L1 antibodies in preclinical models

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作者
Kenkel, Justin A. [1 ]
Gadkari, Rishali [1 ]
Ho, Po Y. [1 ]
Blum, Lisa K. [1 ]
Kudirka, Romas [1 ]
Henning, Karla A. [1 ]
Mallet, William G. [1 ]
Melrose, Jennifer E. [1 ]
Sarma, Ganapathy [1 ]
Chapin, Steven J. [1 ]
Zhou, Matthew [1 ]
Deol, Suprit [1 ]
Kreder, Cindy [1 ]
Shen, Yuyi [1 ]
Hug, Bruce [1 ]
Anand, Puneet [1 ]
Lee, Arthur [1 ]
Li, Hai [1 ]
Ackerman, Shelley E. [1 ]
Safina, Brian S. [1 ]
Dornan, David [1 ]
Alonso, Michael N. [1 ]
Kowanetz, Marcin [1 ]
机构
[1] Bolt Biotherapeut, Redwood City, CA USA
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R73 [肿瘤学];
学科分类号
100214 ;
摘要
4252
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页数:1
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