Antimicrobial resistance in tuberculosis

被引：0
|
作者：
Bautista Gutierrez-Aroca, Juan [1 ]
Ruiz, Pilar [1 ]
Casal, Manuel [1 ]
机构：
[1] Hosp Univ Reina Sofia, Microbiol Serv, Ctr Referencia Control TB, Cordoba, Spain
来源：
REVISTA ESPANOLA DE QUIMIOTERAPIA | 2013年 / 26卷 / 04期
关键词：
tuberculosis; resistance; Mycobacterium; MYCOBACTERIUM-TUBERCULOSIS; RISK;
D O I：
暂无
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Although drug resistance in tuberculosis is by no means a new problem, multiple drug resistance is a cause of increasing concern. This study investigated first-line drug resistance in Mycobacterium tuberculosis strains isolated in a hospital environment and strains submitted as the Reference Center from 2000 to 2010. A total of 650 cultures were tested against first-line using the BACTEC MGIT 960 system. Resistance to first-line drugs was detected in 142 strains, (21.85%). A total of 2% were multiresistant (MDR). Of the strains resistant to first-line drugs, the greatest resistance was found to isoniazid (7.38 %) followed by rifampin and streptomycin (3.85%), pyracinamide (2%), and ethambutol 1.23%. Only one strain was resistant to four drugs. Values. In view of the resistance observed, careful surveillance of drug resistance is recommended.
引用
收藏
页码：332 / 336
页数：5
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