Sulfation made simple: a strategy for synthesising sulfated molecules

被引：26
|
作者：
Gill, Daniel M. [1 ]
Male, Louise [2 ]
Jones, Alan M. [1 ]
机构：
[1] Univ Birmingham, Sch Pharm, Edgbaston B15 2TT, England
[2] Univ Birmingham, Sch Chem, Edgbaston B15 2TT, England
来源：
CHEMICAL COMMUNICATIONS | 2019年 / 55卷 / 30期
关键词：
TERT-BUTYLAMINE COMPLEX; SULFUR-TRIOXIDE; ALIPHATIC-ALCOHOLS; KINETICS; HEPARIN; DIOXIDE;
D O I：
10.1039/c9cc01057b
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The study of organosulfates is a burgeoning area in biology, yet there are significant challenges with their synthesis. We report the development of a tributylsulfoammonium betaine as a high yielding route to organosulfates. The optimised reaction conditions were interrogated with a diverse range of alcohols, including natural products and amino acids.
引用
收藏
页码：4319 / 4322
页数：4
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