LOW-GRADE ASTROCYTOMA CORE MUTATIONS IN IDH1, P53 AND ATRX COOPERATE TO BLOCK DIFFERENTIATION OF HUMAN NEURAL STEM CELLS VIA EPIGENETIC REPRESSION OF SOX2

被引：0

作者：

Modrek, Aram ^{[1
]}

Golub, Danielle ^{[1
]}

Khan, Themasap ^{[1
]}

Prado, Jod ^{[1
]}

Bowman, Christopher ^{[1
]}

Deng, Jingjing ^{[1
]}

Zhang, Guoan ^{[1
]}

Rocha, Pedro ^{[1
]}

Raviram, Ramya ^{[1
]}

Lazaris, Harris ^{[1
]}

Kader, Michael ^{[1
]}

Dhaliwal, Joravar ^{[1
]}

Chi, Andrew ^{[1
]}

Golfinos, John ^{[1
]}

Tsirigos, Aristotelis ^{[1
]}

Zagzag, David ^{[1
]}

Snuderl, Matija ^{[1
]}

Skok, Jane ^{[1
]}

Neubert, Thomas ^{[1
]}

Placantonakis, Dimitris ^{[1
]}

机构：

[1] NYU, Sch Med, New York, NY USA

来源：

NEURO-ONCOLOGY | 2017年 / 19卷

关键词：

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

LGG-11

引用

页码：35 / 35

页数：1

共 8 条

[1] Low-Grade Astrocytoma Mutations in IDH1, P53, and ATRX Cooperate to Block Differentiation of Human Neural Stem Cells via Repression of SOX2
Modrek, Aram S.
Golub, Danielle
Khan, Themasap
Bready, Devin
Prado, Jod
Bowman, Christopher
Deng, Jingjing
Zhang, Guoan
Rocha, Pedro P.
Raviram, Ramya
Lazaris, Charalampos
Stafford, James M.
LeRoy, Gary
Kader, Michael
Dhaliwal, Joravar
Bayin, N. Sumru
Frenster, Joshua D.
Serrano, Jonathan
Chiriboga, Luis
Baitalmal, Rabaa
Nanjangud, Gouri
Chi, Andrew S.
Golfinos, John G.
Wang, Jing
Karajannis, Matthias A.
Bonneau, Richard A.
Reinberg, Danny
Tsirigos, Aristotelis
Zagzag, David
Snuderl, Matija
Skok, Jane A.
Neubert, Thomas A.
Placantonakis, Dimitris G.
CELL REPORTS, 2017, 21 (05): : 1267 - 1280
[2] ASTROCYTOMA MUTATIONS IDH1, p53 AND ATRX COOPERATE TO BLOCK DIFFERENTIATION OF NEURAL STEM CELLS VIA Sox2
Modrek, Aram
Golub, Danielle
Khan, Themasap
Zhang, Guoan
Kader, Michael
Bowman, Christopher
Prado, Jod
Bayin, N. Sumru
Frenster, Joshua
Lhakhang, Tenzin
Heguy, Adriana
Dankert, John
Tsirigos, Aristotelis
Snuderl, Matija
Neubert, Thomas
Placantonakis, Dimitris
NEURO-ONCOLOGY, 2016, 18 : 187 - 187
[3] LOW GRADE ASTROCYTOMA MUTATIONS COOPERATE TO DISRUPT SOX2 GENOMIC ARCHITECTURE AND BLOCK DIFFERENTIATION VIA PREVIOUSLY UNIDENTIFIED ENHANCER ELEMENTS
Bready, Devin
Modrek, Aram
Guerrera, Adler
Frenster, Joshua
Skok, Jane
Placantonakis, Dimitris
NEURO-ONCOLOGY, 2019, 21 : 237 - 237
[4] A Simple Panel of IDH1 and P53 in Differential Diagnosis Between Low-Grade Astrocytoma and Reactive Gliosis
Geramizadeh, Bita
Kohandel-Shirazi, Mahsa
Soltani, Ahmad
CLINICAL PATHOLOGY, 2021, 14
[5] IDH1 MUTATIONS IN NEURAL STEM CELLS PROMOTE MIGRATION AND INVASION AND ACT SYNERGISTICALLY WITH P53 AND PTEN LOSS IN MURINE TUMOUR CELLS
Sidlauskas, Kastytis
Li, Ningning
Lau, Joanne
Ferreira, Andreia
Brandner, Sebastian
NEURO-ONCOLOGY, 2014, 16
[6] Gene expression profile of Sox1, Sox2, p53, Bax and Nestin in neural stem cells and adult mouse brain tissues
Wang, Haifeng
Wang, Kai
Guo, Juan
Wen, Tieqiao
BIOCELL, 2019, 43 (02) : 59 - 64
[7] The prognostic significance of 1p/19q-Deletionen, MGMT Methylation, TP53 and IDH1/2-Mutations for Patients with no adjuvant-treated low-grade Gliomas.
Hartmann, C.
Hentschel, B.
Tonn, J.
Schramm, J.
Westphal, M.
Loeffler, M.
Weller, M.
ONKOLOGIE, 2010, 33 : 54 - 54
[8] Adipose-derived mesenchymal stem cells rescue rat hippocampal cells from aluminum oxide nanoparticle-induced apoptosis via regulation of P53, Aβ, SOX2, OCT4, and CYP2E1
Atia, Mona M.
Alghriany, Alshaimaa A. I.
TOXICOLOGY REPORTS, 2021, 8 : 1156 - 1168

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