Assessment of Coupling and Correlation between Cerebral Autoregulation and Baroreflex in Stroke Patients

Cardiovascular diseases are common nowadays. The main purpose of this research is to integrate the analysis of blood pressure, cerebral blood flow and heart rate to evaluate coupling effect in stroke patients. There are 10 stroke patients (56 +/- 10.6 years) included in this study. Results of blood pressure and cerebral blow velocity values in stroke are lower than those in healthy persons (p<0.05). Low frequency power of blood pressure and cerebral flow velocity are also decreased more than those in healthy subjects (p<0.05), it might be the effect of sympathetic nerve system. K2 means "chaoticness". K2 values of cerebral flow velocity and mean heart rate in stroke subjects are higher than those in healthy subjects significantly (p<0.05), it might indicate cerebral flow and heart rate in stroke are more chaotic. The values of baroreflex sensitivity in healthy subjects are also higher significant (p<0.05). The values of independence of complexity and predictability of blood pressure, cerebral flow and heart rate between 0 and 1 indicate they are highly coupled. Therefore, if the correlation of blood pressure, cerebral flow and heart rate can be observed simultaneously, and the coupling degree of cerebral autoregulation and baroreflex can be investigated, the effect of diagnosis of cardiovascular diseases can be improved.