Magnetically Modified Porous β-Cyclodextrin Polymers for Dispersive Solid-Phase Extraction High-Performance Liquid Chromatography Analysis of Sudan Dyes

Two types of magnetically modified porous beta-cyclodextrin polymers (PCDPs) were successfully synthesized. The first type, named MPCDPs(C), was fabricated by co-precipitating PCDPs with Fe3O4, resulting in a Brunauer-Emmett-Teller (BET) surface area of 106.68 m(2) g(-1). The second type, named MPCDPs(M), was fabricated by grafting PCDPs onto the surface of magnetic microspheres, resulting in a BET surface area of 34.63 m(2) g(-1). Both MPCDPs were found to enable effective extraction and separation of Sudan dyes from foodstuffs and environmental water. Coupled with high-performance liquid chromatography, the limits of detection for Sudan dyes were in the range of 0.013-0.054 ng mL(-1) with MPCDPs(C), and 0.028-0.039 ng mL(-1) with MPCDPs(M). Recoveries were between 85.8 and 102.8% for spiked food samples and 88.3 and 103.2% for spiked water samples, suggesting that the developed methods are promising for accurate quantification of Sudan dyes at trace levels in foodstuffs and environmental water.