Noncovalent Interactions in Organocatalysis: Modulating Conformational Diversity and Reactivity in the MacMillan Catalyst

被引：57
|
作者：
Holland, Mareike C. [1 ,2 ]
Paul, Shyeni [3 ]
Schweizer, W. Bernd [2 ]
Bergander, Klaus [1 ]
Mueck-Lichtenfeld, Christian [1 ]
Lakhdar, Sami [4 ]
Mayr, Herbert [3 ]
Gilmour, Ryan [1 ]
机构：
[1] Univ Munster, Organ Chem Inst, D-48149 Munster, Germany
[2] ETH, Organ Chem Lab, Zurich, Switzerland
[3] Univ Munich, Dept Chem, D-81377 Munich, Germany
[4] ENSICAEN, Lab Chim Mol & Thioorgan, F-14050 Caen, France
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2013年 / 52卷 / 31期
关键词：
conformational analysis; fluorine; imidazolidinone; kinetics; organocatalysis; CATION-PI INTERACTIONS; ORGANIC CATALYSIS; X-RAY; DERIVATIVES; STRATEGIES; PHASE;
D O I：
10.1002/anie.201301864
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Intriguing imidazolidinones! Inspired by noncovalent interactions in proteins, a series of electronically distinct MacMillan catalysts were designed. The effect of electronic modulation on ground state conformation, reactivity, and performance was studied in a catalytic setting with intriguing outcomes. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码：7967 / 7971
页数：5
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