Central nervous system involvement in Wegener's granulomatosis

被引：7
|
作者：
Jouret, F. [1 ]
Noirhomme, S. [1 ]
Grandin, C. [2 ]
Lonneux, M. [3 ]
Godfraind, C. [4 ]
Lambert, M. [1 ]
Lefebvre, C. [1 ]
机构：
[1] Univ Catholique Louvain, Clin Univ St Luc, Serv Med Interne Gen, B-1200 Brussels, Belgium
[2] Univ Catholique Louvain, Clin Univ St Luc, Serv Radiol, B-1200 Brussels, Belgium
[3] Univ Catholique Louvain, Clin Univ St Luc, Nucl Med Serv, B-1200 Brussels, Belgium
[4] Univ Catholique Louvain, Clin Univ St Luc, Serv Anat Pathol, B-1200 Brussels, Belgium
来源：
REVUE DE MEDECINE INTERNE | 2008年 / 29卷 / 11期
关键词：
Vasculitis; Syncope; Positron emission tomography;
D O I：
10.1016/j.revmed.2008.04.003
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Introduction. - Wegener's granulomatosis (WG) is a systemic necrotizing vasculitis associated with c-ANCA antibodies. The involvement of the central nervous system in WG is uncommon and usually caused by in situ vasculitis, intracranial granuloma formation or contiguous invasion from extracranial sites. Case report. - Here, we report on a tumor-like expansion of a severe nasoinusal WG into the brain, which was confirmed by brain biopsy examination. Conclusion. - The positivity of positron emission tomography in our observation supports the potential role of such functional imaging in the staging, as well as in the follow-up of WG. (C) 2008 Publie par Elsevier Masson SAS.
引用
收藏
页码：912 / 916
页数：5
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