Development of the High-throughput Genotoxicity Testing Using a Transcriptomic Biomarker.

被引：0
|
作者：
Li, H-H [1 ]
Chen, R. [2 ]
Aubrecht, J. [1 ]
Fornace, A. J., Jr. [1 ]
机构：
[1] Georgetown Univ, Washington, DC USA
[2] Amelia Technol LLC, Rockville, MD USA
来源：
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS | 2019年 / 60卷
关键词：
D O I：
暂无
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
6
引用
收藏
页码：48 / 49
页数：2
相关论文
共 50 条
  • [1] Genotoxicity Assessment Using In Vitro Micronucleus Assay and a High-Throughput Transcriptomic Biomarker, TGx-DDI.
    Xie, H.
    Kulkarni, R.
    Li, H. H.
    Chen, R.
    Fornace, Jr A. J.
    ENVIRONMENTAL AND MOLECULAR MUTAGENESIS, 2020, 61 : 66 - 66
  • [2] High-throughput testing of genotoxicity of engineered nanomaterials
    Fjellsbo, Lise Marie
    Pran, Elise-Runden
    El Yamani, Naouale
    Dusinska, Maria
    TOXICOLOGY LETTERS, 2015, 238 (02) : S217 - S217
  • [3] A Modern Genotoxicity Testing Paradigm: Integration of the High-Throughput CometChip® and the TGx-DDI Transcriptomic Biomarker in Human HepaRG™ Cell Cultures
    Buick, Julie K.
    Williams, Andrew
    Meier, Matthew J.
    Swartz, Carol D.
    Recio, Leslie
    Gagne, Remi
    Ferguson, Stephen S.
    Engelward, Bevin P.
    Yauk, Carole L.
    FRONTIERS IN PUBLIC HEALTH, 2021, 9
  • [4] Integrated Genotoxicity Testing of three anti-infective drugs using the TGx-DDI transcriptomic biomarker and high-throughput CometChip® assay in TK6 cells
    Buick, Julie K. K.
    Rowan-Carroll, Andrea
    Gagne, Remi
    Williams, Andrew
    Chen, Renxiang
    Li, Heng-Hong
    Fornace Jr, Albert J. J.
    Chao, Christy
    Engelward, Bevin P. P.
    Froetschl, Roland
    Ellinger-Ziegelbauer, Heidrun
    Pettit, Syril D. D.
    Aubrecht, Jiri
    Yauk, Carole L. L.
    FRONTIERS IN TOXICOLOGY, 2022, 4
  • [5] A novel high-throughput enzyme immunoassay for p27Kip1 quantification in drug discovery or as biomarker.
    Zhu, D
    Wang, YD
    Stein, B
    CLINICAL CANCER RESEARCH, 2003, 9 (16) : 6224S - 6225S
  • [6] Development and validation of a high-throughput transcriptomic biomarker to address 21st century genetic toxicology needs
    Li, Heng-Hong
    Chen, Renxiang
    Hyduke, Daniel R.
    Williams, Andrew
    Froetschl, Roland
    Ellinger-Ziegelbauer, Heidrun
    O'Lone, Raegan
    Yauk, Carole L.
    Aubrecht, Jiri
    Fornace, Albert J., Jr.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017, 114 (51) : E10881 - E10889
  • [7] Micronuclei Detection by Flow Cytometry as a High-Throughput Approach for the Genotoxicity Testing of Nanomaterials
    Garcia-Rodriguez, Alba
    Kazantseva, Liliya
    Vila, Laura
    Rubio, Laura
    Velazquez, Antonia
    Jose Ramirez, Maria
    Marcos, Ricard
    Hernandez, Alba
    NANOMATERIALS, 2019, 9 (12)
  • [8] High-throughput micronucleus assay using three-dimensional HepaRG spheroids for in vitro genotoxicity testing
    Seo, Ji-Eun
    Li, Xilin
    Le, Yuan
    Mei, Nan
    Zhou, Tong
    Guo, Xiaoqing
    ARCHIVES OF TOXICOLOGY, 2023, 97 (04) : 1163 - 1175
  • [9] High-throughput micronucleus assay using three-dimensional HepaRG spheroids for in vitro genotoxicity testing
    Ji-Eun Seo
    Xilin Li
    Yuan Le
    Nan Mei
    Tong Zhou
    Xiaoqing Guo
    Archives of Toxicology, 2023, 97 : 1163 - 1175
  • [10] Zebrafish as an In Vivo High-Throughput Model for Genotoxicity
    Chakravarthy, Sridhara
    Sadagopan, Sathish
    Nair, Ayyappan
    Sukumaran, Sunil Kumar
    ZEBRAFISH, 2014, 11 (02) : 154 - 166
12345