Efficient Targeting of T Cell Malignancies In Vitro and In Vivo Using CD4-Specific Chimeric Antigen Receptor (CAR)-Engineered NK Cells

被引：0
|
作者：
Pinz, Kevin G. [1 ]
Yakaboski, Elizabeth [1 ]
Jares, Alexander [2 ]
Liu, Hua [2 ]
Firor, Amelia E. [1 ]
Wada, Masayuki [1 ]
Leung, Lai-Han [3 ]
Jiang, Xun [1 ]
Ma, Yupo [2 ]
机构：
[1] ICell Gene Therapeut LLC, Stony Brook, NY USA
[2] Stony Brook Med, Pathol, Stony Brook, NY USA
[3] Macau Univ Sci & Technol, Inst Appl Res Med, Macau, Peoples R China
来源：
MOLECULAR THERAPY | 2016年 / 24卷
关键词：
D O I：
10.1016/S1525-0016(16)33455-4
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
647
引用
收藏
页码：S256 / S257
页数：2
相关论文
共 50 条
  • [1] Preclinical targeting of human T-cell malignancies using CD4-specific chimeric antigen receptor (CAR)-engineered T cells
    K Pinz
    H Liu
    M Golightly
    A Jares
    F Lan
    G W Zieve
    N Hagag
    M Schuster
    A E Firor
    X Jiang
    Y Ma
    Leukemia, 2016, 30 : 701 - 707
  • [2] Preclinical targeting of human T-cell malignancies using CD4-specific chimeric antigen receptor (CAR)-engineered T cells
    Pinz, K.
    Liu, H.
    Golightly, M.
    Jares, A.
    Lan, F.
    Zieve, G. W.
    Hagag, N.
    Schuster, M.
    Firor, A. E.
    Jiang, X.
    Ma, Y.
    LEUKEMIA, 2016, 30 (03) : 701 - 707
  • [3] Preclinical Targeting of Human Acute Myeloid Leukemia Using CD4-specific Chimeric Antigen Receptor (CAR) T Cells and NK Cells
    Salman, Huda
    Pinz, Kevin G.
    Wada, Masayuki
    Shuai, Xiao
    Yan, Lulu E.
    Petrov, Jessica C.
    Ma, Yupo
    JOURNAL OF CANCER, 2019, 10 (18): : 4408 - 4419
  • [4] Chimeric Antigen Receptor (CAR) T Cells: Lessons Learned from Targeting of CD19 in B-Cell Malignancies
    Hay, Kevin A.
    Turtle, Cameron J.
    DRUGS, 2017, 77 (03) : 237 - 245
  • [5] Chimeric Antigen Receptor (CAR) T Cells: Lessons Learned from Targeting of CD19 in B-Cell Malignancies
    Kevin A. Hay
    Cameron J. Turtle
    Drugs, 2017, 77 : 237 - 245
  • [6] Targeting CD5 chimeric antigen receptor-engineered natural killer cells against T-cell malignancies
    Zu, Yingling
    Ren, Quan
    Zhang, Jishuai
    Su, Hongchang
    Lu, Qiumei
    Song, Yongping
    Zhou, Jian
    EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2024, 13 (01)
  • [7] Precision Targeting of Autoreactive 9G4 B Cells in Systemic Lupus Erythematosus Using Engineered Chimeric Antigen Receptor (CAR)- and Chimeric T Cell Receptor (cTCR)-T Cells
    Liu, Jin
    Mog, Brian
    Xia, Yuanxuan
    Shaw, Elana
    Pearlman, Alexander
    Ferris, Dylan
    Kaeo, Kyle J.
    Gliech, Colin
    Awosika, Tolulope
    Moritz, Brock
    Nichakawade, Tushar
    Li, Yang
    Glavaris, Stephanie
    DiNapoli, Sarah
    Marcou, Nikita
    Ahmedna, Taha
    Alvarado, Victoria Duarte
    Wirtz, Denis
    Bugrovsky, Regina
    Jenks, Scott A.
    Sanz, Inaki
    Goldman, Daniel
    Petri, Michelle
    Bettegowda, Chetan
    Paul, Suman
    Kinzler, Kenneth W.
    Zhou, Shibin
    Andrade, Felipe
    Vogelstein, Bert
    Konig, Maximilian F.
    ARTHRITIS & RHEUMATOLOGY, 2024, 76 : 3575 - 3577
  • [8] Targeting T-cell malignancies using anti-CD4 CAR NK-92 cells
    Pinz, Kevin G.
    Yakaboski, Elizabeth
    Jares, Alexander
    Liu, Hua
    Firor, Amelia E.
    Chen, Kevin H.
    Wada, Masayuki
    Salman, Huda
    Tse, William
    Hagag, Nabil
    Lan, Fengshuo
    Leung, Elaine Lai-Han
    Jiang, Xun
    Ma, Yupo
    ONCOTARGET, 2017, 8 (68) : 112783 - 112796
  • [9] Efficient killing of target cells in vitro by transiently engineered chimeric antigen receptor expressing NK cells
    Meyer, J.
    Meyer, J.
    Morgan, M.
    Falk, C. S.
    Abken, H.
    Schambach, A.
    Galla, M.
    HUMAN GENE THERAPY, 2017, 28 (12) : A26 - A26
  • [10] Chimeric antigen receptor T cells (CAR-T) for the treatment of T-cell malignancies
    Cooper, Mathew L.
    DiPersio, John F.
    BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY, 2019, 32 (04)
12345