Dynamical properties of the reaction-diffusion type model of fast synaptic transport

被引:9
|
作者
Bielecki, Andrzej [1 ]
Kalita, Piotr [1 ]
机构
[1] Jagiellonian Univ, Fac Math & Comp Sci, Inst Comp Sci, PL-30348 Krakow, Poland
关键词
Dynamical system with control; Controllability; Observability; Stability; Averaging; Fast synaptic transport; Parabolic-type partial differential equation; CALCIUM DYNAMICS; LINEAR-SYSTEMS; CONTROLLABILITY; POOL; DEFINITION; GRANULES; SIZE;
D O I
10.1016/j.jmaa.2012.04.012
中图分类号
O29 [应用数学];
学科分类号
070104 ;
摘要
The modulation of a signal that is transmitted in the nerve system takes place in chemical synapses. This article focuses on the phenomena undergone in the presynaptic part of the synapse. A diffusion-reaction type model based on the partial differential equation is proposed. Through an averaging procedure this model is reduced to a model based on ordinary differential equations with control, which is then analyzed according to its dynamical properties-controllability, observability and stability. The system is strongly connected to the one introduced by Aristizabal and Glavinovic (2004)[13]. The biological implications of the obtained mathematical results are also discussed. (C) 2012 Elsevier Inc. All rights reserved.
引用
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页码:329 / 340
页数:12
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