Mechanisms of obesity-induced hypertension

被引:0
|
作者
Hall, JE [1 ]
Zappe, DH [1 ]
AlonsoGalicia, M [1 ]
Granger, JP [1 ]
Brands, MW [1 ]
Kassab, SE [1 ]
机构
[1] MED COLL WISCONSIN, DEPT PHYSIOL, MILWAUKEE, WI 53226 USA
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Q4 [生理学];
学科分类号
071003 ;
摘要
Obesity is a major cause of human essential hypertension. Recent studies point toward increased renal tubular reabsorption and abnormal renal pressure natriuresis in mediating obesity hypertension. The mechanisms for these renal changes appear to be multifactorial, including activation of the sympathetic nervous system and altered intrarenal histology, which compresses the renal medulla.
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页码:255 / 261
页数:7
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