Exocytosis of peptide functionalized gold nanoparticles in endothelial cells

被引：77
|
作者：
Bartczak, Dorota [1 ]
Nitti, Simone [3 ]
Millar, Timothy M. [2 ]
Kanaras, Antonios G. [1 ]
机构：
[1] Univ Southampton, Fac Phys & Appl Sci, Inst Life Sci & Phys & Astron, Southampton SO17 1BJ, Hants, England
[2] Univ Southampton, Fac Med, Southampton SO17 1BJ, Hants, England
[3] Inst Italiano Technol, I-16163 Genoa, Italy
来源：
NANOSCALE | 2012年 / 4卷 / 15期
基金：
英国工程与自然科学研究理事会;
关键词：
CELLULAR UPTAKE; DELIVERY; TOXICITY; SIZE;
D O I：
10.1039/c2nr31064c
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We present the exocytosis profile of two types of peptide-coated nanoparticles, which have similar charge and size but different functionality. While one kind of particles appears to progressively exocytose, the other one has a more complex profile, suggesting that some of the particles are re-uptaken by the cells. Both types of particles retain their colloidal stability after exocytosis.
引用
收藏
页码：4470 / 4472
页数：3
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