Passive control of two merging streams for microfluidic devices

被引:0
|
作者
Kim, SJ [1 ]
Lim, YT [1 ]
Yang, H [1 ]
Shin, YB [1 ]
Kim, K [1 ]
Lee, DS [1 ]
Park, SH [1 ]
Kim, YT [1 ]
机构
[1] ETRI, Biosensor Grp, Taejon 305350, South Korea
来源
关键词
capilarity; microfluids; flow resistance;
D O I
10.1117/12.637730
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
This paper describes the pure passive scheme that manipulates the multiple streams using microfluidic device. This device relies on capillarity to control merging of two streams and to regulate the volumetric flow rate (VFR). This sophisticated manipulation of the capillarity is, however, nontrivial due to the lack of the passive and precise means. Here, we control the capillarity precisely and rapidly through the geometry of the junction of two streams and the hydrophilicity of the substrate. Additionally, we use the relative flow resistance to control the VFR ratio of the merged two streams. This passive scheme leads to the significant simplification of the control of the multistream without sacrificing the rapidity and precision. When combined with the microfluidic components such as mixers, reaction chambers, and detectors, this passive scheme offer the possibility of designing disposable and integrated microfluidic systems.
引用
收藏
页数:7
相关论文
共 50 条
  • [1] Passive microfluidic control of two merging streams by capillarity and relative flow resistance
    Kim, SJ
    Lim, YT
    Yang, HS
    Shin, YB
    Kim, K
    Lee, DS
    Park, SH
    Kim, YT
    ANALYTICAL CHEMISTRY, 2005, 77 (19) : 6494 - 6499
  • [2] A passive pumping method for microfluidic devices
    Walker, GM
    Beebe, DJ
    LAB ON A CHIP, 2002, 2 (03) : 131 - 134
  • [3] Passive microfluidic devices for cell separation
    Zhang, Tianlong
    Di Carlo, Dino
    Lim, Chwee Teck
    Zhou, Tianyuan
    Tian, Guizhong
    Tang, Tao
    Shen, Amy Q.
    Li, Weihua
    Li, Ming
    Yang, Yang
    Goda, Keisuke
    Yan, Ruopeng
    Lei, Cheng
    Hosokawa, Yoichiroh
    Yalikun, Yaxiaer
    BIOTECHNOLOGY ADVANCES, 2024, 71
  • [4] Passive and Active Mixing in Microfluidic Devices
    Meijer, Han E. H.
    Singh, Mrityunjay K.
    Kang, Tae Gong
    den Toonder, Jaap M. J.
    Anderson, Patrick D.
    MACROMOLECULAR SYMPOSIA, 2009, 279 : 201 - 209
  • [5] Passive Droplet Control in Two-Dimensional Microfluidic Networks
    Fink, Gerold
    Hamidovic, Medina
    Wille, Robert
    Haselmayr, Werner
    IEEE TRANSACTIONS ON MOLECULAR BIOLOGICAL AND MULTI-SCALE COMMUNICATIONS, 2019, 5 (03): : 189 - 206
  • [6] Merging the Two Streams of Migration to New Netherland
    Goodfriend, Joyce D.
    NEW YORK HISTORY, 2011, 92 (03) : 133 - 149
  • [7] Electrokinetic fluid control in two-dimensional planar microfluidic devices
    Lerch, Margaret A.
    Jacobson, Stephen C.
    ANALYTICAL CHEMISTRY, 2007, 79 (19) : 7485 - 7491
  • [8] Microfluidic memory and control devices
    Groisman, A
    Enzelberger, M
    Quake, SR
    SCIENCE, 2003, 300 (5621) : 955 - 958
  • [9] Efficient Simulation of Droplet Merging in Channel-based Microfluidic Devices
    Fink, Gerold
    Costamoling, Florina
    Ebner, Philipp
    Wille, Robert
    2023 26TH EUROMICRO CONFERENCE ON DIGITAL SYSTEM DESIGN, DSD 2023, 2023, : 539 - 544
  • [10] A review of passive and active mixing systems in microfluidic devices
    Green, James
    Holdo, Arne E.
    Khan, Aman
    INTERNATIONAL JOURNAL OF MULTIPHYSICS, 2007, 1 (01) : 1 - 32