DSM-5 and RDoC: progress in psychiatry research?

被引：233

作者：

Casey, B. J. ^{[1
]}

Craddock, Nick ^{[2
]}

Cuthbert, Bruce N. ^{[3
]}

Hyman, Steven E. ^{[4
,5
]}

Lee, Francis S. ^{[6
,7
]}

Ressler, Kerry J. ^{[8
,9
]}

机构：

[1] Cornell Univ, Weill Med Coll, Dept Psychiat, Inst Dev Psychobiol, New York, NY 10065 USA

[2] Cardiff Univ, Inst Psychol Med & Clin Neurosci, MRC, Ctr Neuropsychiat Genet & Genom, Cardiff CF24 4HQ, S Glam, Wales

[3] NIMH, NIH, Bethesda, MD 20892 USA

[4] MIT, Stanley Ctr Psychiat Res, Broad Inst, Cambridge, MA 02142 USA

[5] Harvard Univ, Cambridge, MA 02142 USA

[6] Cornell Univ, Weill Cornell Med Coll, Dept Psychiat, New York, NY 10065 USA

[7] Cornell Univ, Weill Cornell Med Coll, Dept Pharmacol, New York, NY 10065 USA

[8] Emory Univ, Howard Hughes Med Inst, Atlanta, GA 30329 USA

[9] Emory Univ, Dept Psychiat & Behav Sci, Atlanta, GA 30329 USA

来源：

NATURE REVIEWS NEUROSCIENCE | 2013年 / 14卷 / 11期

关键词：

FUTURE;

D O I：

10.1038/nrn3621

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Neuroscience studies into psychiatric disorders generally rely on disease definitions that are based on the influential Diagnostic and Statistical Manual of Mental Disorders (DSM), the fifth edition of which (DSM-5) was released earlier this year. Designed as a purely diagnostic tool, the DSM considers different disorders as distinct entities. However, boundaries between disorders are often not as strict as the DSM suggests. To provide an alternative framework for research into psychiatric disorders, the US National Institute of Mental Health (NIMH) has recently introduced its Research Domain Criteria (RDoC) project. In the RDoC, five 'domains' each reflect a brain system in which functioning is impaired, to different degrees, in different psychiatric conditions. Nature Reviews Neuroscience asked six leading investigators for their thoughts on how DSM-5 and the RDoC will influence neuroscience research into psychiatric disorders.

引用

页码：810 / 814

页数：5

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