Human embryonic stem cell-derived extracellular vesicles alleviate retinal degeneration by upregulating Oct4 to promote retinal Muller cell retrodifferentiation via HSP90 (vol 12, 21, 2021)

被引:3
|
作者
Ke, Yifeng [1 ,2 ]
Fan, Xiaoe [3 ]
Hao, Rui [4 ]
Dong, Lijie [1 ,2 ]
Xue, Min [5 ]
Tan, Liangzhang [1 ,2 ]
Yang, Chunbo [1 ,2 ,6 ]
Li, Xiaorong [1 ,2 ]
Ren, Xinjun [1 ,2 ]
机构
[1] Tianjin Med Univ, Eye Inst, Tianjin Int Joint Res & Dev Ctr Ophthalmol & Vis, Tianjin Key Lab Retinal Funct & Dis,Eye Hosp, 251 Fukang Rd, Tianjin 300384, Peoples R China
[2] Tianjin Med Univ, Sch Optometry, Eye Hosp, 251 Fukang Rd, Tianjin 300384, Peoples R China
[3] Jincheng Peoples Hosp, Jincheng 048000, Shanxi, Peoples R China
[4] Tianjin Med Univ, Nankai Univ Eye Hosp, Tianjin Eye Hosp, Clin Coll Ophthalmol, Tianjin, Peoples R China
[5] Anhui 2 Prov Peoples Hosp, Dept Ophthalmol, Hefei 230000, Anhui, Peoples R China
[6] Newcastle Univ, Inst Med Genet, Cent Pkwy, Newcastle Upon Tyne NE1 3BZ, Tyne & Wear, England
基金
中国国家自然科学基金;
关键词
HSP90; Human embryonic stem extracellular vesicle; Microvesicle; Oct4; Retinal degeneration; Retinal Müller cell; Retrodifferentiation;
D O I
10.1186/s13287-021-02213-z
中图分类号
Q813 [细胞工程];
学科分类号
摘要
An amendment to this paper has been published and can be accessed via the original article.
引用
收藏
页数:1
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