Genetic and pharmacologic evidence implicating the p85-alphs, but not p85-beta, regulatory subunit of PI-3kinase and Rac2 GTPase in regulating oncogenic KIT induced transformation in acute myeloid leukemia and systemic mastocytosis

被引:0
|
作者
Munugalavadla, V. [1 ]
Sims, E. C. [1 ]
Kapur, R. [1 ]
机构
[1] Indiana Univ, Indianapolis, IN 46204 USA
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:75 / 75
页数:1
相关论文
共 5 条
  • [1] Genetic and pharmacologic evidence implicating the p85α, but not p85β, regulatory subunit of PI-3Kinase and Rac2 GTPase in regulating oncogenic kit induced transformation in acute myeloid leukemia and systemic mastocytosis.
    Munugalavadla, V.
    Sims, E. C.
    Kapur, R.
    PEDIATRIC RESEARCH, 2007, 62 (04) : 519 - 519
  • [2] Genetic and pharmacologic evidence implicating the p85α, but not p85β, regulatory subunit of PI3K and Rac2 GTPase in regulating oncogenic KIT-induced transformation in acute myeloid leukemia and systemic mastocytosis
    Munugalavadla, Veerendra
    Sims, Emily C.
    Borneo, Jovencio
    Chan, Rebecca J.
    Kapur, Reuben
    BLOOD, 2007, 110 (05) : 1612 - 1620
  • [3] Requirement for p85α regulatory subunit of class IA PI3kinase and rac2 GTPase in myeloproliferative disease driven by activation loop mutant of KIT
    Munugalavadla, Veerendra
    Sims, Emily C.
    Lenz, Stephen D.
    Kapur, Reuben
    BLOOD, 2007, 110 (11) : 35A - 35A
  • [4] DECLINED PRESENTATION P21-ACTIVATED KINASE AND GUANINE EXCHANGE FACTORS FOR RAC GTPASES IN ONCOGENIC KIT INDUCED SYSTEMIC MASTOCYTOSIS AND ACUTE MYELOID LEUKEMIA
    Martin, Holly
    Mali, Raghuveer
    Ma, Peilin
    Chatterjee, Anindya
    Vlaar, Cornelis
    Ramdas, Baskar
    Dharmawardhane, Suraganie
    Visconte, Valeria
    Tiu, Ramon
    Kapur, Reuben
    EXPERIMENTAL HEMATOLOGY, 2013, 41 (08) : S56 - S56
  • [5] Role of p21 Activated Kinase and Specific Guanine Exchange Factors of Rac Gtpases in Oncogenic KIT Induced Systemic Mastocytosis and Acute Myeloid Leukemia
    Martin, Holly
    Ma, Peilin
    Chatterjee, Anindya
    Ramdas, Baskar
    Sims, Emily
    Vlaar, Cornelis
    Dharmawardhane, Suraganie
    Kapur, Reuben
    BLOOD, 2012, 120 (21)