HIV, Pregnancy, and Isoniazid Preventive Therapy

被引：4

作者：

Tiendrebeogo, Thierry ^{[1
]}

Anglaret, Xavier ^{[2
]}

Becquet, Renaud ^{[3
]}

机构：

[1] Univ Bordeaux, Bordeaux, France

[2] Programme PAC CI, Abidjan, Cote Ivoire

[3] INSERM, Unite 1219, Bordeaux, France

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2020年 / 382卷 / 12期

关键词：

D O I：

10.1056/NEJMc1916664

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

To the Editor: Gupta et al. (Oct. 3 issue)(1) report a higher incidence of adverse pregnancy outcomes among women with human immunodeficiency virus (HIV) infection who were exposed to isoniazid preventive therapy (IPT) during the second and third trimesters than among those not exposed to IPT during pregnancy. From 2007 through 2015, we conducted a randomized, controlled trial (TEMPRANO ANRS 12136) to evaluate the benefits and risks of 6-month IPT (vs. no IPT) and immediate antiretroviral therapy (ART) (vs. deferred ART) in 2052 West African adults.(2,3) During trial follow-up, 85 women became pregnant, including 14 who had voluntary abortions and . . .

引用

页码：1184 / 1184

页数：1

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