Leukemia Cell Mobilization with Plerixafor Plus G-CSF with Busulfan/Fludarabine and Allogeneic Hematopoietic Cell Transplantation in Patients with AML/MDS Is Associated with Decreased Complete Chimerism and GvHD, and Increased Risk of Relapse

被引:1
|
作者
Benton, Christopher B. [1 ]
Konopleva, Marina
Saliba, Rima M.
Shpall, Elizabeth J.
Ciurea, Stefan O. [2 ]
Kebriaei, Partow [2 ]
Alousi, Amin M. [2 ]
Popat, Uday R. [2 ]
Anderlini, Paolo [2 ]
Nieto, Yago [2 ]
Parmar, Simrit
Zeng, Zhihong [3 ]
Chen, Julianne J.
Rondon, Gabriela [2 ]
McMullin, Becky
Wang, Rui-Yu
Lu, Hongbo [3 ]
Schober, Wendy D. [3 ]
Woodworth, Glenda G.
Gulbis, Alison [4 ]
Cool, Rita [4 ]
Qiao, Wei [5 ]
Thall, Peter F.
Andreeff, Michael
Champlin, Richard E.
机构
[1] Univ Texas MD Anderson Canc Ctr, Div Canc Med, Houston, TX 77030 USA
[2] Univ Texas MD Anderson Canc Ctr, Dept Stem Cell Transplantat & Cellular Therapy, Houston, TX 77030 USA
[3] Univ Texas MD Anderson Canc Ctr, Dept Leukemia, Sect Mol Hematol & Therapy, Houston, TX 77030 USA
[4] Univ Texas MD Anderson Canc Ctr, Dept Stem Cell Transplantat & Cellular Therapy, Houston, TX 77030 USA
[5] Univ Texas MD Anderson Canc Ctr, Dept Biostat, Houston, TX 77030 USA
关键词
D O I
10.1182/blood.V120.21.360.360
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
360
引用
收藏
页数:2
相关论文
共 50 条
  • [1] Leukemia cell mobilization with G-CSF plus plerixafor during busulfan–fludarabine conditioning for allogeneic stem cell transplantation
    M Konopleva
    C B Benton
    P F Thall
    Z Zeng
    E Shpall
    S Ciurea
    P Kebriaei
    A Alousi
    U Popat
    P Anderlini
    Y Nieto
    S Parmar
    W Qiao
    J Chen
    G Rondon
    B McMullin
    R-Y Wang
    H Lu
    W Schober
    G Woodworth
    A Gulbis
    R Cool
    M Andreeff
    R Champlin
    Bone Marrow Transplantation, 2015, 50 : 939 - 946
  • [2] Leukemia cell mobilization with G-CSF plus plerixafor during busulfan-fludarabine conditioning for allogeneic stem cell transplantation
    Konopleva, M.
    Benton, C. B.
    Thall, P. F.
    Zeng, Z.
    Shpall, E.
    Ciurea, S.
    Kebriaei, P.
    Alousi, A.
    Popat, U.
    Anderlini, P.
    Nieto, Y.
    Parmar, S.
    Qiao, W.
    Chen, J.
    Rondon, G.
    McMullin, B.
    Wang, R-Y
    Lu, H.
    Schober, W.
    Woodworth, G.
    Gulbis, A.
    Cool, R.
    Andreeff, M.
    Champlin, R.
    BONE MARROW TRANSPLANTATION, 2015, 50 (07) : 939 - 946
  • [3] Hematopoietic, Immune Recovery and Outcomes after Autologous Stem Cell Transplantation Following Plerixafor Plus G-CSF Versus Chemotherapy and G-CSF Based Mobilization in Pediatric Patients
    Choi, Jung Yoon
    Kang, Hyoung Jin
    Hong, Kyung Taek
    Hong, Che Ry
    Park, Kyung Duk
    Shin, Hee Young
    BLOOD, 2017, 130
  • [4] Highly sensitive chimerism detection in blood is associated with increased risk of relapse after allogeneic hematopoietic cell transplantation in childhood leukemia
    Haugaard, Anna Karen
    Madsen, Hans Ole
    Marquart, Hanne Vibeke
    Rosthoj, Susanne
    Masmas, Tania Nicole
    Heilmann, Carsten
    Mueller, Klaus Gottlob
    Ifversen, Marianne
    PEDIATRIC TRANSPLANTATION, 2019, 23 (07)
  • [5] DECLINE IN DONOR LYMPHOID CHIMERISM PRECEDING ACUTE MYELOID LEUKEMIA RELAPSE FOLLOWING ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION CONDITIONED WITH BUSULFAN AND FLUDARABINE
    Van Damme, Danielle
    Ghanim, Majd
    Savasan, Sureyya
    PEDIATRIC BLOOD & CANCER, 2015, 62 : 118 - 118
  • [6] Proteomic Profiling Identifies c-KIT and 53BP1 As Resistance Factors of AML Relapse Post Allogeneic Stem Cell Transplantation with G-CSF/Plerixafor/Busulfan-Fludarabine Conditioning
    Zeng, Zhihong
    Lu, Hongbo
    Wang, Rui-Yu
    Lu, Wenbin
    Chen, Julianne
    Benton, Christopher B.
    Baggerly, Keith
    Shpall, Elizabeth J.
    Champlin, Richard E.
    Konopleva, Marina
    Andreeff, Michael
    BLOOD, 2017, 130
  • [7] Proteomic Profiling of Signaling Networks Modulated by G-CSF/Plerixafor/Busulfan-Fludarabine Conditioning in Acute Myeloid Leukemia Patients in Remission or with Active Disease prior to Allogeneic Stem Cell Transplantation
    Zeng, Zhihong
    Liu, Wenbin
    Benton, Christopher B.
    Konoplev, Sergej
    Lu, Hongbo
    Wang, Rui-Yu
    Chen, Julianne
    Shpall, Elizabeth
    Baggerly, Keith A.
    Champlin, Richard
    Konopleva, Marina
    ACTA HAEMATOLOGICA, 2019, 142 (03) : 176 - 184
  • [8] AN EFFECTIVE HEMATOPOIETIC STEM CELL MOBILIZATION ALGORITHM FOR ADDING PLERIXAFOR TO G-CSF FOR MULTIPLE MYELOMA PATIENTS UNDERGOING AUTOLOGOUS TRANSPLANTATION
    LaPorte, J.
    Solomon, S.
    Bashey, A.
    Holland, K.
    Morris, L.
    Sizemore, C.
    Sanacore, M.
    Mihelic, R.
    Leech, M.
    Penland, P.
    Xang, Z.
    BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2012, 18 (02) : S379 - S380
  • [9] On demand plerixafor is safe and effective for hematopoietic progenitor cell mobilization in patients with light chain amyloidosis at risk for mobilization failure with G-CSF alone
    Hubben, Anne
    Dima, Danai
    Atieh, Tahani
    Chaulagain, Chakra
    Faiman, Beth
    Ferraro, Christina
    Mazzoni, Sandra
    Williams, Louis
    Samaras, Christy
    Valent, Jason
    Sauter, Craig
    Anwer, Faiz
    Khouri, Jack
    BONE MARROW TRANSPLANTATION, 2023, 58 (05) : 610 - 612
  • [10] On demand plerixafor is safe and effective for hematopoietic progenitor cell mobilization in patients with light chain amyloidosis at risk for mobilization failure with G-CSF alone
    Anne Hubben
    Danai Dima
    Tahani Atieh
    Chakra Chaulagain
    Beth Faiman
    Christina Ferraro
    Sandra Mazzoni
    Louis Williams
    Christy Samaras
    Jason Valent
    Craig Sauter
    Faiz Anwer
    Jack Khouri
    Bone Marrow Transplantation, 2023, 58 : 610 - 612