Tumor-associated extracellular vesicles from HPV plus oropharyngeal cancer lymphatic fluid trigger an anti-tumor response through activation of the cGAS-STING pathway

被引：0
|
作者：
Xu, Zhongping
Earland, Noah
Harris, Peter K.
Gerndt, Sophie P.
Ramirez, Ricardo
Semenkovich, Nicholas P.
Chaudhuri, Aadel A.
Zevallos, Jose P.
机构：
来源：
CLINICAL CANCER RESEARCH | 2023年 / 29卷 / 18期
关键词：
D O I：
10.1158/1557-3265.AACRAHNS23-PO-097
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
PO-097
引用
收藏
页数：2
相关论文
共 21 条
  • [1] Targeting cGAS-STING pathway for reprogramming tumor-associated macrophages to enhance anti-tumor immunotherapy
    Zhang, Weiyue
    Huang, Xin
    BIOMARKER RESEARCH, 2025, 13 (01)
  • [2] Tumor- intrinsic cGAS-STING activation promotes anti-tumor inflammatory response in osteosarcoma
    Young, Elizabeth Betsy Peale
    Johnson, Christine
    Lee, Alex G.
    Sweet-Cordero, Eric Alejandro
    CANCER RESEARCH, 2024, 84 (06)
  • [3] cGAS-STING activation promotes anti-tumor inflammatory response in osteosarcoma: Implications for tumor microenvironment reprogramming and tumor progression in patients
    Young, Elizabeth P.
    Johnson, Christine A.
    Lee, Alex G.
    Schott, Courtney R.
    Sweet-Cordero, E. Alejandro
    CANCER IMMUNOLOGY RESEARCH, 2023, 11 (12)
  • [4] Zebularine potentiates anti-tumor immunity by inducing tumor immunogenicity and improving antigen processing through cGAS-STING pathway
    Zhang, Yong
    Zhao, Heng
    Deng, Weili
    Lai, Junzhong
    Sang, Kai
    Chen, Qi
    COMMUNICATIONS BIOLOGY, 2024, 7 (01)
  • [5] DUAL ACTIVATION OF THE CGAS-STING PATHWAY AND AIM2-INDUCED PYROPTOSIS BY TUMOR-TREATING FIELDS PRODUCES ANTI-TUMOR IMMUNITY IN GLIOBLASTOMA
    Chen, Dongjiang
    Sebastian, Mathew
    Hutchinson, Tarun
    Ghiaseddin, Ashley
    Warren, Sonisha
    Allen, Annie
    Jin, Dan
    Le, Son
    Tran, David
    NEURO-ONCOLOGY, 2020, 22 : 113 - 114
  • [6] Carbon Ion Radiotherapy Exerts Anti-Tumor Activity by Inducing cGAS-STING Activation and Immune Response in Prostate Cancer-Bearing Mice
    Hu, W.
    Zhang, Z.
    Zhang, Q.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2023, 117 (02): : E236 - E236
  • [7] Activation of STING inhibits cervical cancer tumor growth through enhancing the anti-tumor immune response
    Fan Shi
    Jin Su
    Juan Wang
    Zi Liu
    Tao Wang
    Molecular and Cellular Biochemistry, 2021, 476 : 1015 - 1024
  • [8] Activation of STING inhibits cervical cancer tumor growth through enhancing the anti-tumor immune response
    Shi, Fan
    Su, Jin
    Wang, Juan
    Liu, Zi
    Wang, Tao
    MOLECULAR AND CELLULAR BIOCHEMISTRY, 2021, 476 (02) : 1015 - 1024
  • [9] Chitosan-based nano-micelles for potential anti-tumor immunotherapy: Synergistic effect of cGAS-STING signaling pathway activation and tumor antigen absorption
    Zhang, Shufen
    Zeng, Yingping
    Wang, Kai
    Song, Guangtao
    Yu, Yiru
    Meng, Tingting
    Yuan, Hong
    Hu, Fuqiang
    CARBOHYDRATE POLYMERS, 2023, 321
  • [10] RETRACTED: Siglec-15 Regulates the Inflammatory Response and Polarization of Tumor-Associated Macrophages in Pancreatic Cancer by Inhibiting the cGAS-STING Signaling Pathway (Retracted Article)
    Li, HuaGen
    Zhu, RongXuan
    Liu, XiaoLong
    Zhao, Kai
    Hong, DeFei
    OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2022, 2022
123